Skin Boosters in Korea: Rejuran, Juvelook & More — Complete Comparison Guide

If you have ever wondered how Korean celebrities and influencers maintain that impossibly dewy, translucent "glass skin," the answer often lies beneath the surface — literally. Skin boosters are injectable treatments that work from the inside out, delivering active ingredients directly into the dermis to hydrate, repair, and rejuvenate the skin at a cellular level. South Korea is the global epicenter for these treatments, offering unmatched variety, competitive pricing, and world-class dermatologists who perform thousands of these procedures every week.

This guide breaks down everything you need to know about getting skin booster treatments in Korea as an international visitor in 2026 — from how each product works to what you should expect to pay.

What Are Skin Boosters?

Unlike traditional fillers that add volume to specific areas, skin boosters are micro-injections of bioactive substances delivered across a wider area of the face (or body). Their goal is not to reshape your features but to improve overall skin quality from within — think hydration, elasticity, texture, and glow.

A typical skin booster session involves dozens of tiny injections across the cheeks, forehead, under-eyes, or neck. The procedure takes 20 to 40 minutes, and most patients experience only mild redness and small bumps that subside within 24 to 48 hours.

Korean dermatology clinics have pioneered several distinct categories of skin boosters, each using different active ingredients to target different skin concerns. The four most popular options are Rejuran, Juvelook, Profhilo, and classic HA (hyaluronic acid) skin boosters like Restylane Skinboosters.

The Big Four: Skin Booster Types Compared

Rejuran Healer (Salmon DNA / PN)

Rejuran is arguably Korea's most iconic skin booster and the treatment most closely associated with the "Korean glow." Its key ingredient is polynucleotide (PN), extracted from salmon DNA (specifically salmon sperm cells). Before you raise an eyebrow — PN is a well-studied biomolecule that mimics the structure of human DNA and has powerful skin-regenerating properties.

How it works: Once injected into the dermis, PN stimulates fibroblast activity, promoting natural wound healing and collagen production. It also has anti-inflammatory properties that help calm sensitive or damaged skin.

Best for: Dry, thin, or sensitive skin; redness and irritation; overall skin health restoration; fine lines and dullness.

Sessions needed: 3 sessions at 2 to 3 week intervals for optimal results, with maintenance every 3 to 6 months.

Variations: Rejuran Healer (standard), Rejuran HB (added hyaluronic acid for extra hydration), Rejuran i (formulated for the delicate under-eye area), and Rejuran S (scar treatment).

Juvelook (PDLLA + Hyaluronic Acid)

Juvelook is a newer-generation skin booster that has rapidly gained popularity in Korean clinics. It combines poly-D,L-lactic acid (PDLLA) with hyaluronic acid, offering both immediate hydration and long-term collagen stimulation.

How it works: The hyaluronic acid component provides instant moisture, while PDLLA microparticles gradually break down in the skin over weeks to months, stimulating fibroblasts to produce new collagen. This dual-action mechanism means you get both short-term glow and long-term structural improvement.

Best for: Enlarged pores; acne scars; skin laxity and loss of firmness; fine wrinkles; patients aged 30 and above seeking collagen regeneration.

Sessions needed: 3 sessions at 3 to 4 week intervals. Results can last up to 18 months with a full course.

Variations: Juvelook (standard 2cc), Juvelook Volume (higher PDLLA concentration for deeper volumizing and lifting).

Profhilo (Hybrid Hyaluronic Acid)

Originally developed in Italy, Profhilo has become a staple in premium Korean clinics. It contains an exceptionally high concentration of hyaluronic acid (64mg per 2ml syringe) — the highest on the market — using a patented NAHYCO technology that combines high-molecular-weight and low-molecular-weight HA without chemical cross-linking.

How it works: Rather than staying in one spot like a filler, Profhilo disperses evenly through the tissue, acting as a "bio-remodeler." It stimulates the production of four types of collagen plus elastin, leading to significant improvements in skin firmness, hydration, and elasticity.

Best for: Skin laxity on face and neck; mature skin (40+); patients wanting a lifting and tightening effect without fillers; overall skin rejuvenation.

Sessions needed: 2 sessions one month apart. Effects peak at 4 to 6 weeks and last 6 to 9 months.

Classic HA Skin Boosters (Restylane Skinboosters / Teosyal Redensity)

These are the original skin boosters — stabilized hyaluronic acid formulations injected in micro-doses across the face. Brands like Restylane Vital and Teosyal Redensity I remain popular for their straightforward hydrating effect.

How it works: Micro-droplets of cross-linked HA are deposited in the superficial dermis, where they attract and hold water to plump and hydrate the skin from within.

Best for: General dehydration; first-time skin booster patients; maintaining results between more intensive treatments.

Sessions needed: 3 initial sessions at 2 to 4 week intervals, with maintenance every 4 to 6 months.

Price Comparison: Skin Boosters in Seoul (2026)

One of the biggest advantages of getting skin boosters in Korea is the price. Treatments here cost a fraction of what you would pay in the US, Europe, or Australia. Below is a comparison based on current Seoul clinic pricing.

Note: Prices vary significantly between clinics. Gangnam and Cheongdam clinics tend to charge premium rates, while clinics in Myeongdong and Hongdae often offer competitive pricing for international patients. Many clinics also offer package discounts when you book a full course of 3 sessions upfront — savings of 15 to 30 percent are common.

Which Skin Booster Is Right for You?

Choosing the right skin booster depends on your specific skin concerns, age, budget, and how long you will be staying in Korea.

• Dry, sensitive, or damaged skin: Start with Rejuran Healer. Its PN base is unmatched for skin repair, hydration, and calming inflammation. It is the best "foundation" treatment for overall skin health.

• Enlarged pores, acne scars, or early aging: Choose Juvelook. The collagen-stimulating PDLLA component addresses structural concerns that pure hydration cannot fix, and the results are long-lasting.

• Mature skin with laxity: Go with Profhilo. Its bio-remodeling action provides the most dramatic firming and lifting effect among skin boosters, and it requires only two sessions.

• First timer on a budget: Try Restylane Skinboosters or Rejuran HB for a solid introduction to injectable skin hydration at a lower price point.

• Comprehensive rejuvenation: Many Korean dermatologists recommend combination protocols — for example, Rejuran for repair followed by Juvelook for collagen building — tailored to your individual skin analysis.

Recommended Clinics in Seoul

Several Seoul clinics are well-regarded for skin booster treatments among international patients:

• Lienjang Clinic — Branches in Gangnam, Hongdae, and Myeongdong. Known for transparent pricing and English-speaking staff. Popular with medical tourists for its accessible locations.

• WOOA Dermatology (Gangnam) — A specialist dermatology clinic in Gangnam offering a wide range of skin boosters with detailed skin analysis consultations.

• Three Wishes Clinic (Myeongdong) — Located one minute from Myeongdong Station Exit 9. High patient satisfaction ratings and convenient for visitors staying in central Seoul.

• BAILOR Clinic (Cheongdam) — A premium aesthetic clinic in the upscale Cheongdam neighborhood, offering customized skin booster cocktail protocols.

Tip: Many clinics offer free consultations. Book consultations at 2 to 3 clinics before committing, and always confirm pricing in advance. International patients in Korea can also claim a VAT refund at the airport, which provides an additional saving.

Tips for International Visitors

1. Book ahead. Popular clinics fill up fast, especially during peak tourist seasons (spring and autumn). Reserve your first session before arriving in Korea.

2. Plan your schedule. If you need 3 sessions spaced 2 to 3 weeks apart, you will need at least 6 weeks in Korea — or plan to complete the first session during one trip and return for follow-ups.

3. Bring your medical history. Some skin boosters (particularly Rejuran) are derived from biological materials. Inform your doctor about any allergies, especially to fish or seafood.

4. Expect mild downtime. Small bumps and redness are normal for 1 to 2 days. Avoid heavy makeup, alcohol, saunas, and intense exercise for 24 to 48 hours post-treatment.

5. Use booking platforms. Apps like Gangnam Unni and Yeoshin Ticket often feature promotional pricing for skin boosters, and some include English-language interfaces and reviews.

Frequently Asked Questions

How painful are skin booster injections?

Most clinics apply a topical numbing cream 20 to 30 minutes before the procedure. You may feel a series of tiny pricks, but most patients describe the discomfort as very manageable — around a 3 out of 10 on a pain scale.

Can I combine different skin boosters in one session?

Yes. Many Korean dermatologists specialize in "cocktail protocols" that layer different skin boosters — for example, Rejuran for the full face plus Juvelook targeted at acne scars. Discuss combination options during your consultation.

How soon will I see results?

Rejuran and HA skin boosters show initial hydration improvements within a few days. Juvelook and Profhilo results build gradually over 2 to 6 weeks as collagen production increases. Full results are typically visible after completing the recommended course.

Is there anyone who should avoid skin boosters?

Skin boosters are generally safe, but they are not recommended for pregnant or breastfeeding women, individuals with active skin infections at the injection site, or those with severe allergies to any of the ingredients. Rejuran should be avoided by people with fish or seafood allergies.

Are Korean skin boosters safe?

All major skin booster brands used in Korean clinics (Rejuran, Juvelook, Profhilo, Restylane) are approved by the Korean Ministry of Food and Drug Safety (MFDS). Korea has some of the strictest cosmetic procedure regulations in the world, and licensed dermatologists perform these treatments daily with an excellent safety track record.

How much can I save compared to getting skin boosters in my home country?

Depending on your location, you can save 40 to 70 percent by getting skin boosters in Korea. A Rejuran session that costs $600 to $800 in the US or Australia typically costs $250 to $370 in Seoul. When combined with the quality of care and expertise available, Korea offers exceptional value.

Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Skin booster treatments are medical procedures that carry potential risks and side effects including bruising, swelling, infection, and allergic reactions. Always consult with a licensed dermatologist or medical professional before undergoing any cosmetic procedure. Individual results may vary. The prices listed are approximate and subject to change — always confirm current pricing directly with the clinic.