Rejuran Skin Booster in Korea: Complete Guide to PDRN Treatment, Prices & Results 2025

24 min readBy Seoul Skin Guide Team
Rejuran Skin Booster in Korea: Complete Guide to PDRN Treatment, Prices & Results 2025
#rejuran#pdrn#skin booster#skin healing#anti-aging

Rejuran Skin Booster in Korea: Complete Guide to PDRN Treatment, Prices & Results 2025

If you've been researching Korean skincare treatments, you've likely encountered Rejuran—one of the most popular and talked-about skin boosters in Seoul's dermatology scene. This revolutionary treatment harnesses the healing power of PDRN (Polynucleotide) derived from salmon DNA to fundamentally repair and rejuvenate your skin from within.

Known as "리쥬란" (ri-jyu-ran) in Korean, Rejuran represents a completely different approach to skin improvement—rather than simply adding hydration or stimulating collagen, it actually helps your skin cells heal and regenerate at a DNA level.

Korean skincare treatment close-up

What is Rejuran?

Rejuran is a injectable skin booster treatment that uses PDRN (Polydeoxyribonucleotide)—a DNA fragment extracted from salmon—to promote skin healing, reduce inflammation, and stimulate regeneration. Unlike other skin boosters that focus solely on hydration or collagen stimulation, Rejuran works at the cellular level to repair damaged skin and restore its natural vitality.

The Science: What is PDRN?

PDRN (Polydeoxyribonucleotide) is a biopolymer composed of DNA building blocks extracted from salmon sperm. But why salmon?

The Salmon Connection:

  • Salmon DNA is remarkably similar to human DNA (approximately 95% compatible)
  • High biocompatibility means minimal rejection risk
  • Naturally promotes tissue repair and regeneration
  • Has been used in medical wound healing for decades

How Rejuran Works: The Mechanism

When PDRN is injected into your skin, it triggers multiple beneficial effects:

1. Cellular Regeneration:

  • Activates fibroblast cells (the "factory" that produces collagen and elastin)
  • Stimulates DNA synthesis and cell proliferation
  • Accelerates wound healing and tissue repair
  • Helps damaged cells recover and function normally

2. Anti-Inflammatory Action:

  • Reduces chronic inflammation that accelerates aging
  • Calms irritated, sensitive skin
  • Improves conditions like rosacea and redness
  • Decreases inflammatory acne

3. Angiogenesis (Blood Vessel Formation):

  • Promotes new blood vessel formation
  • Improves circulation and oxygen delivery
  • Enhances nutrient supply to skin cells
  • Results in healthier, more radiant complexion

4. Antioxidant Protection:

  • Protects cells from free radical damage
  • Reduces oxidative stress
  • Slows cellular aging process

5. Moisture Retention:

  • Improves skin's natural moisture-binding capacity
  • Enhances barrier function
  • Results in hydrated, plump skin

This multifaceted approach makes Rejuran particularly effective for compromised, damaged, or prematurely aging skin.

Rejuran Family: Different Types Explained

Korean clinics offer several Rejuran formulations, each optimized for specific concerns:

1. Rejuran Healer (Original)

What It Is: The original PDRN skin booster formula

Best For:

  • Overall skin quality improvement
  • Anti-aging and prevention
  • Skin healing and repair
  • Reducing inflammation
  • Fine lines and wrinkles
  • Sensitive, irritated skin

Injection Method: Multiple micro-injections across the face (nappage technique)

Typical Amount: 2-4cc per session

Pain Level: 5-6/10 (many small injections can be uncomfortable)

Price Range: ₩150,000-₩320,000 ($115-$246) per session

2. Rejuran HB (Healer Booster)

What It Is: Rejuran Healer + Hyaluronic Acid

Key Difference: Adds non-crosslinked HA for immediate hydration and glow

Best For:

  • Dry, dehydrated skin
  • Those wanting immediate "glass skin" effect
  • Combination of healing + instant hydration
  • Dull, tired-looking skin

Advantages:

  • Immediate glow from HA
  • Long-term healing from PDRN
  • Dual-action formula

Price Range: ₩180,000-₩350,000 ($138-$269) per session (typically 10-20% more than Healer)

3. Rejuran I (Eye)

What It Is: Specialized formula for delicate under-eye area

Key Features:

  • Lower concentration, gentler formula
  • Smaller injection volume
  • Designed for thin periorbital skin

Best For:

  • Under-eye fine lines
  • Dark circles improvement
  • Eye area skin quality
  • Delicate eye area rejuvenation

Typical Amount: 1cc per session (both eyes)

Price Range: ₩150,000-₩280,000 ($115-$215) per session

4. Rejuran S (Scar)

What It Is: High-concentration formula for targeted scar treatment

Key Features:

  • Higher PDRN concentration
  • Thicker consistency
  • Targeted injection into scars

Best For:

  • Acne scars (atrophic, rolling)
  • Surgical scars
  • Traumatic scars
  • Stubborn textural irregularities

Price Range: ₩200,000-₩400,000 ($154-$308) per session

5. Rejuran Tone-up Booster

What It Is: Rejuran + brightening ingredients (glutathione, tranexamic acid)

Best For:

  • Pigmentation concerns
  • Dull skin tone
  • Uneven complexion
  • Combined healing + brightening

Price Range: ₩200,000-₩380,000 ($154-$292) per session

Quick Comparison Table

TypeMain BenefitBest ForPrice (USD)
HealerOverall healing & regenerationGeneral anti-aging$115-$246
HBHealing + hydrationDry skin, instant glow$138-$269
I (Eye)Eye area rejuvenationUnder-eye concerns$115-$215
S (Scar)Scar improvementAcne/surgical scars$154-$308
Tone-upHealing + brighteningPigmentation$154-$292

Most Korean patients start with Rejuran Healer or HB for overall improvement, then add specialized versions (Eye, Scar) as needed.

Woman receiving facial injection treatment

Rejuran Prices in Korea 2025

Rejuran pricing varies based on type, amount used, and clinic location.

Rejuran Healer Pricing

Per Session:

  • Budget Range: ₩94,272 - ₩130,000 ($73 - $100 USD)
  • Mid-Range: ₩150,000 - ₩220,000 ($115 - $169 USD)
  • Premium Clinics: ₩250,000 - ₩320,708 ($192 - $247 USD)

Average Price: ₩165,575 (~$127 USD) per session

Per cc Pricing:

  • Average: ₩121,000 (~$93 USD) per cc
  • Typical treatment uses 2cc (₩242,000 / $186)

Package Pricing (Recommended)

Korean dermatologists typically recommend 3-4 sessions for optimal results:

3-Session Package:

  • Price: ₩400,000 - ₩700,000 ($308 - $538 USD)
  • Spacing: 2-4 weeks apart
  • Discount: 15-25% off individual pricing

4-Session Package:

  • Price: ₩500,000 - ₩900,000 ($385 - $692 USD)
  • Spacing: 2-4 weeks apart
  • Discount: 20-30% off individual pricing

5-Session Package:

  • Price: ₩600,000 - ₩1,100,000 ($462 - $846 USD)
  • Spacing: 2-4 weeks apart
  • Maximum cumulative benefits

Pricing by Rejuran Type (per session)

Rejuran TypeSeoul Average (USD)Gangnam Premium (USD)
Healer (2cc)$115-$169$192-$247
HB (2cc)$138-$200$215-$292
Eye (1cc)$115-$169$169-$215
S Scar (per treatment)$154-$231$231-$308
Tone-up (2cc)$154-$215$215-$292

What Affects Rejuran Pricing?

  1. Amount Used:

    • 2cc (standard full face): Base price
    • 3cc (full face + neck): 1.5x price
    • 4cc (comprehensive coverage): 2x price
  2. Rejuran Type:

    • Healer: Standard pricing
    • HB: 10-20% premium (HA addition)
    • Specialized versions (Eye, Scar, Tone-up): Variable premium
  3. Clinic Location:

    • Gangnam/Apgujeong: 30-50% higher
    • Other Seoul districts: Average
    • Suburban areas: 20-30% lower
  4. Injection Method:

    • Hand injection (traditional): Standard price
    • Injector gun (less painful): May cost ₩20,000-50,000 more
    • Sleep Rejuran (under sedation): Significant premium
  5. Doctor vs. Nurse:

    • Dermatologist-performed: Higher price, better technique
    • Nurse-administered (supervised): Lower price

Korea vs. USA Price Comparison

TreatmentSeoul (USD)Los Angeles (USD)New York (USD)Savings
Single Rejuran Session (2cc)$115-$169$600-$1,200$700-$1,50075-85%
3-Session Package$308-$538$1,500-$3,000$1,800-$3,50070-80%
Rejuran HB (2cc)$138-$200$700-$1,400$800-$1,60075-85%

Prices as of November 2025. Exchange rate: ₩1,300 ≈ $1 USD. Actual costs vary by clinic and treatment specifics.

Rejuran is dramatically more affordable in Korea, where it was developed and first introduced. Korean clinics also have the most experience administering PDRN treatments.

Treatment Results: What to Expect

Understanding Rejuran's gradual, healing-focused results is key to proper expectations.

Immediate Effects (Day 0-7): First Impressions

Right After Treatment:

  • Multiple small injection bumps (papules) across face
  • Redness and slight swelling
  • Possible minor bruising
  • Warmth in treated areas

First 24-48 Hours:

  • Bumps flatten as product distributes
  • Swelling peaks and subsides
  • Skin may feel tight or sensitive
  • Immediate hydration glow (especially with HB formula)

First Week:

  • 59% of patients notice effects immediately according to Korean clinic data
  • Skin feels softer, smoother, more supple
  • Improved skin texture
  • "Bouncy" skin quality
  • Enhanced radiance

Real patient feedback: "The morning after my first Rejuran treatment, I thought I'd been reborn. My face felt incredibly soft and hydrated. The glow was real!"

Short-Term Healing (Weeks 2-4): Cellular Regeneration Begins

Week 2:

  • 36% of patients report effects appearing by week 1
  • Gradual improvement in skin quality
  • Reduced inflammation and redness
  • Pores appear smaller
  • Fine lines begin to soften

Week 3-4:

  • Skin elasticity noticeably improves
  • More even skin tone
  • Reduced sensitivity
  • Healthier overall appearance
  • Makeup applies more smoothly

Korean dermatologists emphasize: "Watch for gradual changes over 2 weeks, not overnight miracles."

Long-Term Transformation (Months 2-6): Maximum Benefits

Month 2-3:

  • 5% of patients don't see significant effects until one month
  • Maximum skin healing and regeneration
  • Dramatic improvement in:
    • Skin texture and smoothness
    • Fine lines and wrinkles
    • Pore size
    • Overall skin health
    • Radiance and vitality

Month 3-6:

  • Results plateau and maintain
  • Skin continues to look healthy and youthful
  • Preventive anti-aging benefits
  • Foundation for long-term skin health

Real patient review: "I did 3 Rejuran sessions, one month apart. By month 2-3, my skin quality was completely different—smoother, bouncier, healthier. Even my dermatologist was impressed!"

Duration of Results

Single Session:

  • Immediate effects: 1-2 weeks
  • Skin quality improvement: 2-3 months

Treatment Series (3-4 sessions):

  • Cumulative regeneration: Results last 6-12 months
  • Some patients report benefits lasting up to 18 months
  • Each treatment builds on previous foundation

Maintenance Strategy:

  • Annual or bi-annual treatment series
  • Quarterly single sessions
  • Combination with other treatments

Expected Improvement Percentages

Based on Korean patient reviews and clinic data:

  • Skin texture: 60-80% improvement
  • Fine lines: 40-60% reduction
  • Skin elasticity: 50-70% improvement
  • Redness/inflammation: 70-90% reduction
  • Overall skin quality: 70-85% of patients report significant satisfaction
  • Pore size: 30-50% reduction

The Rejuran Treatment Experience

What Happens During Your Appointment

Step 1: Consultation (15-30 minutes)

  • Skin assessment and concern discussion
  • Determination of appropriate Rejuran type
  • Amount recommendation (2cc, 3cc, 4cc)
  • Pricing and package options

Step 2: Cleansing (5 minutes) Thorough facial cleansing to remove all impurities.

Step 3: Numbing Cream (20-30 minutes)

  • Topical anesthetic applied to entire face
  • Essential for comfort (Rejuran involves many injections)
  • Korean clinics use high-quality numbing products

Step 4: Rejuran Injection (15-30 minutes)

Traditional Hand Injection (most common):

  • Nappage technique: Multiple shallow injections across entire face
  • 50-100+ injection points depending on coverage
  • Each injection deposits small amount of product
  • Creates even distribution across treatment area

Injection Gun Method (newer, more comfortable):

  • Automated multi-needle device
  • Faster treatment time
  • More even product distribution
  • Less painful than hand injection
  • Costs ₩20,000-50,000 more

What It Feels Like:

  • With numbing: 4-5/10 (multiple pinpricks, tolerable)
  • Without numbing: 7-8/10 (not recommended)
  • More injections = more cumulative discomfort
  • Bony areas (forehead, jawline) more sensitive

Step 5: Massage and Cooling (5-10 minutes)

  • Gentle massage to distribute product evenly
  • Cooling mask to reduce redness and swelling
  • Soothing serum application

Step 6: Post-Treatment Care (5 minutes)

  • Moisturizer and SPF application
  • Aftercare instructions
  • Photography (optional)

Total Appointment Time: 60-90 minutes

Pain and Discomfort Level

Pain Rating: Most patients rate Rejuran 5-6/10 with numbing

Why More Uncomfortable Than Other Boosters:

  • Many more injection points (50-100 vs. 20-40 for other treatments)
  • Cumulative discomfort from multiple pricks
  • PDRN has thicker viscosity than pure HA
  • Some formulations can sting slightly

Comparison:

  • More painful than: Aqua skin boosters, simple HA injections
  • About same as: Juvelook, some mesotherapy treatments
  • Less painful than: Microneedling RF, aggressive laser treatments

Korean Comfort Solutions:

  • Premium numbing creams
  • Injection gun for faster, more comfortable treatment
  • "Sleep Rejuran" (under sedation) for extremely sensitive patients
  • Ice packs before and after
  • Distraction techniques

Korean aesthetic clinic interior

Side Effects and Recovery

Rejuran is considered very safe with minimal serious side effects when properly administered.

Common, Expected Side Effects

Immediately After (0-24 hours):

  • Multiple small bumps (papules) at each injection site (completely normal)
  • Redness: Moderate, fades within 4-24 hours
  • Swelling: Mild to moderate, peaks at 12-24 hours
  • Tenderness: Skin feels sensitive to touch
  • Warmth: Treated areas feel warm

Days 2-7:

  • Bumps flatten within 1-3 days as product distributes
  • Possible bruising: 20-30% of patients experience minor bruising
  • Tightness: Skin may feel firm as healing begins
  • Dryness: Temporary, improves with moisturizer

These are normal healing responses and indicate the treatment is working.

Less Common Side Effects

  • Prolonged swelling: Lasting 3-7 days (rare)
  • Visible lumps: If product doesn't distribute evenly (massage helps)
  • Increased sensitivity: Heightened reaction to skincare products temporarily
  • Temporary redness: Lasting several days in very sensitive skin
  • Itching: As healing progresses (don't scratch!)

Rare but Possible Complications

  • Infection: Extremely rare with proper sterile technique
  • Allergic reaction: Very rare (PDRN is highly biocompatible)
  • Vascular complications: Extremely rare with experienced injectors
  • Granuloma formation: Very rare delayed reaction
  • Persistent bumps: May require hyaluronidase (for HB version) or time to resolve

Who Should Avoid Rejuran?

Absolute Contraindications:

  • Pregnancy or breastfeeding
  • Active skin infection or inflammation
  • Allergy to salmon or seafood (PDRN is salmon-derived!)
  • Open wounds in treatment area
  • History of severe allergic reactions to injectables

Relative Contraindications (Consult Doctor):

  • Autoimmune disorders
  • Immunosuppressive medications
  • Recent facial surgery (wait 3-6 months)
  • Active severe acne
  • Blood clotting disorders
  • History of keloid scarring

Important: If you have a seafood allergy, inform your doctor. While PDRN is highly purified, caution is warranted.

Post-Treatment Care: Maximizing Results

Proper aftercare optimizes healing and results.

First 24-48 Hours: Critical Window

DO:

  • ✅ Apply ice packs (10-15 minutes every 2-3 hours) for swelling
  • ✅ Sleep with head elevated (reduces swelling)
  • ✅ Drink plenty of water (supports healing)
  • ✅ Use gentle, fragrance-free cleanser
  • ✅ Apply prescribed soothing cream
  • ✅ Take arnica supplements (reduces bruising)

DON'T:

  • ❌ Touch, rub, or massage treated areas (first 6 hours)
  • ❌ Apply makeup for 12-24 hours
  • ❌ Use hot water on face
  • ❌ Exercise or activities causing sweating (24-48 hours)
  • ❌ Consume alcohol (increases swelling and bruising)
  • ❌ Sleep face-down (can affect product distribution)

First Week Care

Skincare Routine:

  • Gentle cleanser (lukewarm water only)
  • Hydrating toner/essence
  • Moisturizer (ceramide-rich recommended)
  • SPF 50+ sunscreen (critical!)

Activities to Avoid:

  • ❌ Vigorous exercise (wait 48-72 hours)
  • ❌ Saunas, steam rooms, hot baths (wait 1 week)
  • ❌ Facial massage (wait 1 week)
  • ❌ Other facial treatments (lasers, peels, microneedling) - wait 2-4 weeks
  • ❌ Dental work (wait 1-2 weeks)
  • ❌ Strong acids, retinol (wait 3-5 days)

Ongoing Care (Weeks 2-4 and Beyond)

Support Skin Healing:

  • Gentle skincare: No harsh exfoliants or aggressive treatments
  • Hydration: 2-3 liters water daily
  • Sun protection: UV damage undoes healing (SPF 50+ daily)
  • Adequate sleep: 7-9 hours for cellular repair
  • Healthy diet: Antioxidants, vitamins, protein
  • No smoking: Destroys collagen and impairs healing

Enhance Results:

  • Vitamin C serum (after 1 week): Supports collagen production
  • Peptide products: Enhance skin repair
  • Sheet masks: Popular in Korea, maintain hydration
  • Quality moisturizer: Support barrier function

Between Treatment Sessions

If doing a series (recommended):

  • Schedule 2-4 weeks apart for optimal cumulative effect
  • Maintain consistent gentle skincare
  • Avoid sun damage between sessions
  • Track progress with photos (same lighting)
  • Communicate any concerns to your doctor

Rejuran vs. Other Skin Treatments

Understanding how Rejuran compares helps you choose the right treatment.

Rejuran vs. Juvelook

FeatureRejuranJuvelook
Main IngredientPDRN (Polynucleotide)PDLA + Hyaluronic Acid
Primary ActionSkin healing & regenerationCollagen stimulation + hydration
Best ForDamaged, sensitive, inflamed skinPores, texture, volume
MechanismDNA-level cellular repairCollagen building
Immediate GlowModerateStrong (HA component)
Results Timeline1-4 weeks4-12 weeks
Duration6-12 months9-12 months
Pain Level5-6/10 (many injections)3-4/10 (fewer injections)
Price (Korea)$115-$169/session$192-$308/session

Choose Rejuran if: You have sensitive, damaged, or inflamed skin needing healing Choose Juvelook if: You want pore refinement and structural improvement

Rejuran vs. Aqua Skin Booster

FeatureRejuranAqua Skin Booster
TechnologyPDRN (DNA healing)HA + vitamins + peptides
Primary GoalSkin healing & anti-agingHydration & glow
Depth of ActionCellular level (DNA)Surface to mid-dermis
Best ForSkin repair, inflammationImmediate glow, hydration
Durability6-12 months3-6 months
Sessions Needed3-4 recommended1-3 sufficient for glow
PriceHigherLower

Choose Rejuran if: You want fundamental skin healing and long-term improvement Choose Aqua Booster if: You want quick hydration and glass skin effect

Rejuran vs. PRP (Platelet-Rich Plasma)

FeatureRejuran (PDRN)PRP (Vampire Facial)
SourceSalmon DNA (standardized)Your own blood
ConsistencyStandardized potencyVariable (depends on your blood quality)
ProcedureDirect injectionBlood draw + processing + injection
Time Required60-90 minutes90-120 minutes
DowntimeMild (bumps, redness)Moderate (more intense redness)
ResultsPredictable, consistentVariable by individual
Price (Korea)$115-$169$200-$400

Choose Rejuran if: You want standardized, predictable results Choose PRP if: You prefer autologous (own tissue) treatments

Real Patient Reviews from Korea

Highly Satisfied Patients

"I did 4 Rejuran Healer sessions for my sensitive, irritated skin. After years of redness and inflammation, my skin finally calmed down. It's now smooth, bouncy, and healthy-looking. Life-changing treatment!"

"At 52, my skin was thin, dull, and tired. Three Rejuran HB sessions later, I have this youthful glow and plumpness I haven't seen in years. Friends think I've had a facelift!"

"Rejuran Eye completely transformed my under-eye area. The fine lines are so much softer, dark circles improved, and the skin looks healthier. Worth every won!"

Moderately Satisfied

"Rejuran definitely improved my skin texture and reduced my redness. Results were good but gradual—I needed to be patient. Not the dramatic overnight change I hoped for, but solid long-term improvement."

"Did 3 sessions and my skin is nicer—smoother, more hydrated, healthier. But the improvement is subtle. I think my expectations were too high based on Instagram before/afters."

"The treatment helped with my acne scars and improved my skin quality overall. Results are good but required multiple sessions and maintenance. It's more of a long-term investment than a quick fix."

Mixed or Disappointed

"Spent ₩500,000 on 3 sessions and honestly can't see much difference. My skin feels slightly better, but no visible improvement in my concerns. Maybe PDRN just doesn't work for everyone."

"The injections were really uncomfortable—so many tiny pricks. Results were okay but not worth the pain and cost for me. I got better results from lasers."

"Had an allergic reaction (I have seafood allergies, which I didn't connect to salmon-derived PDRN). Developed itching and bumps that lasted 2 weeks. My fault for not mentioning my allergies!"

Common Themes in Reviews

  • Patience essential: Results are gradual, not immediate
  • Best for sensitive/damaged skin: Dramatic improvement for compromised skin
  • Multiple sessions crucial: 1 session gives minimal lasting results
  • Discomfort factor: Many injections = more uncomfortable than some treatments
  • Healing focus: Different from volumizing or dramatic lifting
  • Korean clinics most experienced: Treatment originated in Korea

Choosing the Right Clinic in Seoul

Red Flags to Avoid

Extremely Low Prices: Authentic Rejuran under ₩100,000 ($77) is suspicious

Can't Verify Product: Genuine Rejuran has specific packaging from Pharma Research

No Patch Test Offered: Important for those with sensitive skin or allergies

Vague "PDRN Treatment" Claims: Verify it's genuine Rejuran, not generic PDRN

No Consultation: Reputable clinics assess suitability first

Pressure Tactics: Forcing large package purchases immediately

What to Look For

Authentic Rejuran: Verify product packaging (made by Pharma Research Co.)

Experienced Injector: Board-certified dermatologist preferred

Customized Treatment: Type and amount tailored to your concerns

Realistic Expectations: Honest about gradual results timeline

Before/After Photos: Real patient results from that clinic

English Communication: Essential for discussing concerns

Proper Numbing: Quality anesthetic for comfort

Transparent Pricing: Clear costs with no hidden fees

Best Areas for Rejuran in Seoul

Gangnam (강남):

  • Most experienced Rejuran practitioners
  • Premium service and expertise
  • Price: ₩200,000-₩320,000/session ($154-$247)
  • Best for: Complex cases, maximum expertise

Apgujeong (압구정):

  • High-quality clinics
  • Celebrity clientele
  • Price: ₩170,000-₩280,000/session ($131-$215)
  • Best for: Quality + competitive pricing

Sinsa-dong (신사동):

  • Modern boutique clinics
  • Mid-range pricing
  • Price: ₩150,000-₩240,000/session ($115-$185)
  • Best for: Good value

Myeongdong (명동):

  • Tourist-friendly
  • English support common
  • Price: ₩130,000-₩220,000/session ($100-$169)
  • Best for: Convenient access

Hongdae (홍대):

  • Budget-friendly options
  • Younger crowd
  • Price: ₩100,000-₩180,000/session ($77-$138)
  • Best for: Value seekers

Questions to Ask During Consultation

  1. Is this authentic Rejuran? (Ask to see the packaging)
  2. Which Rejuran type do you recommend for my concerns?
  3. How much product (cc) do I need?
  4. How many sessions do you recommend?
  5. Do you use hand injection or injection gun?
  6. What are the risks for my skin type?
  7. I have seafood allergies—is Rejuran safe for me?
  8. What's included in the price?
  9. Can I see before/after photos of similar cases?
  10. What's your protocol if complications occur?

Tips for International Visitors

Planning Your Rejuran Trip to Seoul

Timeline Considerations:

  • Minimum stay: 1 week (allows for 1-2 treatments)
  • Ideal stay: 3-4 weeks (allows 2-3 treatments spaced properly)
  • Alternative: Get 1-2 treatments during visit, continue at home if available

Scheduling Strategy:

  1. Contact clinics 2-3 weeks ahead
  2. Confirm authentic Rejuran and pricing
  3. Schedule first treatment early in trip
  4. Avoid important events within 2-3 days (bumps and swelling)
  5. Space sessions 2-4 weeks apart if doing multiple

What to Bring

  • Passport or ID
  • Cash and credit cards (cash discounts common)
  • List of allergies (especially seafood!)
  • Current medications list
  • Photos showing concerns
  • Comfortable mask (for covering bumps when leaving)

Post-Treatment Travel

Flying After Rejuran:

  • Safe to fly after initial swelling subsides (24-48 hours)
  • Bumps may still be visible but not painful
  • Stay hydrated during flight
  • Avoid alcohol on plane
  • Continue gentle skincare

Managing Side Effects While Traveling:

  • Ice packs or hotel ice for swelling
  • Arnica gel and supplements
  • Gentle, fragrance-free skincare products
  • Mineral makeup to cover bumps (after 24 hours)
  • Plan indoor activities for first 2-3 days

Frequently Asked Questions

Q: Does Rejuran hurt? A: With numbing cream, most patients rate it 5-6/10—tolerable but noticeable due to many injection points. The injection gun method is more comfortable than traditional hand injection.

Q: How many treatments do I need? A: Korean dermatologists typically recommend 3-4 sessions spaced 2-4 weeks apart for optimal cumulative healing. Mild concerns may improve with 2 sessions; damaged or mature skin benefits from 4-5 treatments.

Q: When will I see results? A: 59% of patients notice effects immediately (hydration, glow). Gradual healing improvements appear over 2-4 weeks, with maximum results at 2-3 months as cellular regeneration completes.

Q: Is Rejuran safe if I have seafood allergies? A: Inform your doctor about seafood allergies. While PDRN is highly purified and most seafood-allergic patients tolerate it well, caution is appropriate. A patch test may be recommended.

Q: Rejuran or Juvelook—which is better? A: Different purposes. Rejuran: Best for skin healing, reducing inflammation, repairing damage. Juvelook: Best for pore refinement, structural improvement, volumizing. Rejuran focuses on healing; Juvelook on building.

Q: Can Rejuran treat acne scars? A: Yes! Rejuran S (Scar formula) is specifically designed for acne scar treatment. Regular Rejuran Healer also improves mild scarring. Expect 30-50% improvement over 3-4 sessions for mild to moderate scars.

Q: What's the difference between Rejuran Healer and HB? A: Rejuran HB adds hyaluronic acid for immediate hydration and glow. Healer is pure PDRN focused on healing. HB provides instant glass skin effect plus long-term healing; Healer is gradual improvement only.

Q: How long do results last? A: With a series of 3-4 treatments, results typically last 6-12 months, sometimes up to 18 months. Annual or bi-annual maintenance sessions help sustain benefits.

Q: Can I combine Rejuran with other treatments? A: Yes! Commonly combined with lasers, Botox, fillers, and other skin boosters. Your doctor will advise on timing—some can be done same day, others need 2-4 weeks spacing.

Q: Will the bumps be visible? A: Yes, multiple small bumps will be visible for 12-48 hours after treatment. They're very noticeable immediately after but flatten significantly within 24 hours. Plan accordingly for social events.

Is Rejuran Worth It? Final Verdict

Rejuran represents a fundamentally different approach to skin improvement—working at the DNA level to heal and regenerate rather than simply plumping or stimulating. For the right candidate, it offers genuine, lasting skin quality improvement.

Rejuran is Worth It If:

✅ You have damaged, sensitive, or inflamed skin needing healing ✅ You prefer biological, regenerative treatments ✅ You can commit to 3-4 treatment sessions for cumulative results ✅ You're patient with gradual improvement over weeks ✅ You value long-term skin health over quick fixes ✅ You want to address underlying skin quality, not just surface issues ✅ You're seeking preventive anti-aging treatment ✅ You can tolerate multiple injections and temporary bumps

Consider Alternatives If:

❌ You have severe seafood allergies (consult doctor first) ❌ You want immediate, dramatic volumizing (fillers better) ❌ You need quick results for an upcoming event ❌ You can't tolerate many injections ❌ Your budget is very limited (single sessions give minimal lasting results) ❌ You want primarily hydration (simpler boosters cheaper) ❌ You're looking for dramatic lifting (consider Ulthera or threads)

Conclusion

Rejuran has revolutionized Korean skincare by introducing PDRN-based cellular healing to aesthetic medicine. As one of the first and most researched salmon DNA treatments, Rejuran offers scientifically-backed skin regeneration that goes beyond surface-level improvements.

Korea remains the ideal destination for Rejuran treatment—it was developed here, Korean dermatologists have the most experience administering it, and prices are 75-85% lower than Western countries. The variety of Rejuran formulations (Healer, HB, Eye, Scar, Tone-up) allows for customized treatment addressing specific concerns.

The key to Rejuran success lies in choosing an experienced clinic with authentic products, completing a full treatment series (3-4 sessions), setting realistic expectations about gradual results, and supporting healing through proper skincare and lifestyle. While the multiple injections can be uncomfortable and initial bumps are visible, the majority of Korean patients report high satisfaction with natural, lasting skin quality improvement.

Ready to heal and rejuvenate your skin at the cellular level? Research clinics thoroughly, verify authentic Rejuran products, discuss your allergies and concerns openly, and prepare for a gradual but genuine transformation in your skin's health and vitality.


⚠️ Medical Disclaimer: This article provides general information about Rejuran PDRN skin booster treatment in Korea. It is not intended as medical advice. Results vary significantly based on individual factors including age, skin condition, lifestyle, and natural healing capacity. Rejuran carries risks including allergic reactions (especially in those with seafood allergies), swelling, bruising, infection, and other complications. Not all patients are suitable candidates, and results are not guaranteed. PDRN is derived from salmon—inform your doctor of any seafood or fish allergies. Always consult with a board-certified dermatologist before undergoing any cosmetic procedure. Discuss your complete medical history, allergies, medications, expectations, and concerns during your consultation.


Last Updated: November 22, 2025 Reading Time: 19 minutes

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