Rejuran Skin Booster in Korea: Complete Guide to PDRN Treatment, Prices & Results 2025
If you've been researching Korean skincare treatments, you've likely encountered Rejuran—one of the most popular and talked-about skin boosters in Seoul's dermatology scene. This revolutionary treatment harnesses the healing power of PDRN (Polynucleotide) derived from salmon DNA to fundamentally repair and rejuvenate your skin from within.
Known as "리쥬란" (ri-jyu-ran) in Korean, Rejuran represents a completely different approach to skin improvement—rather than simply adding hydration or stimulating collagen, it actually helps your skin cells heal and regenerate at a DNA level.
What is Rejuran?
Rejuran is a injectable skin booster treatment that uses PDRN (Polydeoxyribonucleotide)—a DNA fragment extracted from salmon—to promote skin healing, reduce inflammation, and stimulate regeneration. Unlike other skin boosters that focus solely on hydration or collagen stimulation, Rejuran works at the cellular level to repair damaged skin and restore its natural vitality.
The Science: What is PDRN?
PDRN (Polydeoxyribonucleotide) is a biopolymer composed of DNA building blocks extracted from salmon sperm. But why salmon?
The Salmon Connection:
- Salmon DNA is remarkably similar to human DNA (approximately 95% compatible)
- High biocompatibility means minimal rejection risk
- Naturally promotes tissue repair and regeneration
- Has been used in medical wound healing for decades
How Rejuran Works: The Mechanism
When PDRN is injected into your skin, it triggers multiple beneficial effects:
1. Cellular Regeneration:
- Activates fibroblast cells (the "factory" that produces collagen and elastin)
- Stimulates DNA synthesis and cell proliferation
- Accelerates wound healing and tissue repair
- Helps damaged cells recover and function normally
2. Anti-Inflammatory Action:
- Reduces chronic inflammation that accelerates aging
- Calms irritated, sensitive skin
- Improves conditions like rosacea and redness
- Decreases inflammatory acne
3. Angiogenesis (Blood Vessel Formation):
- Promotes new blood vessel formation
- Improves circulation and oxygen delivery
- Enhances nutrient supply to skin cells
- Results in healthier, more radiant complexion
4. Antioxidant Protection:
- Protects cells from free radical damage
- Reduces oxidative stress
- Slows cellular aging process
5. Moisture Retention:
- Improves skin's natural moisture-binding capacity
- Enhances barrier function
- Results in hydrated, plump skin
This multifaceted approach makes Rejuran particularly effective for compromised, damaged, or prematurely aging skin.
Rejuran Family: Different Types Explained
Korean clinics offer several Rejuran formulations, each optimized for specific concerns:
1. Rejuran Healer (Original)
What It Is: The original PDRN skin booster formula
Best For:
- Overall skin quality improvement
- Anti-aging and prevention
- Skin healing and repair
- Reducing inflammation
- Fine lines and wrinkles
- Sensitive, irritated skin
Injection Method: Multiple micro-injections across the face (nappage technique)
Typical Amount: 2-4cc per session
Pain Level: 5-6/10 (many small injections can be uncomfortable)
Price Range: ₩150,000-₩320,000 ($115-$246) per session
2. Rejuran HB (Healer Booster)
What It Is: Rejuran Healer + Hyaluronic Acid
Key Difference: Adds non-crosslinked HA for immediate hydration and glow
Best For:
- Dry, dehydrated skin
- Those wanting immediate "glass skin" effect
- Combination of healing + instant hydration
- Dull, tired-looking skin
Advantages:
- Immediate glow from HA
- Long-term healing from PDRN
- Dual-action formula
Price Range: ₩180,000-₩350,000 ($138-$269) per session (typically 10-20% more than Healer)
3. Rejuran I (Eye)
What It Is: Specialized formula for delicate under-eye area
Key Features:
- Lower concentration, gentler formula
- Smaller injection volume
- Designed for thin periorbital skin
Best For:
- Under-eye fine lines
- Dark circles improvement
- Eye area skin quality
- Delicate eye area rejuvenation
Typical Amount: 1cc per session (both eyes)
Price Range: ₩150,000-₩280,000 ($115-$215) per session
4. Rejuran S (Scar)
What It Is: High-concentration formula for targeted scar treatment
Key Features:
- Higher PDRN concentration
- Thicker consistency
- Targeted injection into scars
Best For:
- Acne scars (atrophic, rolling)
- Surgical scars
- Traumatic scars
- Stubborn textural irregularities
Price Range: ₩200,000-₩400,000 ($154-$308) per session
5. Rejuran Tone-up Booster
What It Is: Rejuran + brightening ingredients (glutathione, tranexamic acid)
Best For:
- Pigmentation concerns
- Dull skin tone
- Uneven complexion
- Combined healing + brightening
Price Range: ₩200,000-₩380,000 ($154-$292) per session
Quick Comparison Table
| Type | Main Benefit | Best For | Price (USD) |
|---|---|---|---|
| Healer | Overall healing & regeneration | General anti-aging | $115-$246 |
| HB | Healing + hydration | Dry skin, instant glow | $138-$269 |
| I (Eye) | Eye area rejuvenation | Under-eye concerns | $115-$215 |
| S (Scar) | Scar improvement | Acne/surgical scars | $154-$308 |
| Tone-up | Healing + brightening | Pigmentation | $154-$292 |
Most Korean patients start with Rejuran Healer or HB for overall improvement, then add specialized versions (Eye, Scar) as needed.
Rejuran Prices in Korea 2025
Rejuran pricing varies based on type, amount used, and clinic location.
Rejuran Healer Pricing
Per Session:
- Budget Range: ₩94,272 - ₩130,000 ($73 - $100 USD)
- Mid-Range: ₩150,000 - ₩220,000 ($115 - $169 USD)
- Premium Clinics: ₩250,000 - ₩320,708 ($192 - $247 USD)
Average Price: ₩165,575 (~$127 USD) per session
Per cc Pricing:
- Average: ₩121,000 (~$93 USD) per cc
- Typical treatment uses 2cc (₩242,000 / $186)
Package Pricing (Recommended)
Korean dermatologists typically recommend 3-4 sessions for optimal results:
3-Session Package:
- Price: ₩400,000 - ₩700,000 ($308 - $538 USD)
- Spacing: 2-4 weeks apart
- Discount: 15-25% off individual pricing
4-Session Package:
- Price: ₩500,000 - ₩900,000 ($385 - $692 USD)
- Spacing: 2-4 weeks apart
- Discount: 20-30% off individual pricing
5-Session Package:
- Price: ₩600,000 - ₩1,100,000 ($462 - $846 USD)
- Spacing: 2-4 weeks apart
- Maximum cumulative benefits
Pricing by Rejuran Type (per session)
| Rejuran Type | Seoul Average (USD) | Gangnam Premium (USD) |
|---|---|---|
| Healer (2cc) | $115-$169 | $192-$247 |
| HB (2cc) | $138-$200 | $215-$292 |
| Eye (1cc) | $115-$169 | $169-$215 |
| S Scar (per treatment) | $154-$231 | $231-$308 |
| Tone-up (2cc) | $154-$215 | $215-$292 |
What Affects Rejuran Pricing?
-
Amount Used:
- 2cc (standard full face): Base price
- 3cc (full face + neck): 1.5x price
- 4cc (comprehensive coverage): 2x price
-
Rejuran Type:
- Healer: Standard pricing
- HB: 10-20% premium (HA addition)
- Specialized versions (Eye, Scar, Tone-up): Variable premium
-
Clinic Location:
- Gangnam/Apgujeong: 30-50% higher
- Other Seoul districts: Average
- Suburban areas: 20-30% lower
-
Injection Method:
- Hand injection (traditional): Standard price
- Injector gun (less painful): May cost ₩20,000-50,000 more
- Sleep Rejuran (under sedation): Significant premium
-
Doctor vs. Nurse:
- Dermatologist-performed: Higher price, better technique
- Nurse-administered (supervised): Lower price
Korea vs. USA Price Comparison
| Treatment | Seoul (USD) | Los Angeles (USD) | New York (USD) | Savings |
|---|---|---|---|---|
| Single Rejuran Session (2cc) | $115-$169 | $600-$1,200 | $700-$1,500 | 75-85% |
| 3-Session Package | $308-$538 | $1,500-$3,000 | $1,800-$3,500 | 70-80% |
| Rejuran HB (2cc) | $138-$200 | $700-$1,400 | $800-$1,600 | 75-85% |
Prices as of November 2025. Exchange rate: ₩1,300 ≈ $1 USD. Actual costs vary by clinic and treatment specifics.
Rejuran is dramatically more affordable in Korea, where it was developed and first introduced. Korean clinics also have the most experience administering PDRN treatments.
Treatment Results: What to Expect
Understanding Rejuran's gradual, healing-focused results is key to proper expectations.
Immediate Effects (Day 0-7): First Impressions
Right After Treatment:
- Multiple small injection bumps (papules) across face
- Redness and slight swelling
- Possible minor bruising
- Warmth in treated areas
First 24-48 Hours:
- Bumps flatten as product distributes
- Swelling peaks and subsides
- Skin may feel tight or sensitive
- Immediate hydration glow (especially with HB formula)
First Week:
- 59% of patients notice effects immediately according to Korean clinic data
- Skin feels softer, smoother, more supple
- Improved skin texture
- "Bouncy" skin quality
- Enhanced radiance
Real patient feedback: "The morning after my first Rejuran treatment, I thought I'd been reborn. My face felt incredibly soft and hydrated. The glow was real!"
Short-Term Healing (Weeks 2-4): Cellular Regeneration Begins
Week 2:
- 36% of patients report effects appearing by week 1
- Gradual improvement in skin quality
- Reduced inflammation and redness
- Pores appear smaller
- Fine lines begin to soften
Week 3-4:
- Skin elasticity noticeably improves
- More even skin tone
- Reduced sensitivity
- Healthier overall appearance
- Makeup applies more smoothly
Korean dermatologists emphasize: "Watch for gradual changes over 2 weeks, not overnight miracles."
Long-Term Transformation (Months 2-6): Maximum Benefits
Month 2-3:
- 5% of patients don't see significant effects until one month
- Maximum skin healing and regeneration
- Dramatic improvement in:
- Skin texture and smoothness
- Fine lines and wrinkles
- Pore size
- Overall skin health
- Radiance and vitality
Month 3-6:
- Results plateau and maintain
- Skin continues to look healthy and youthful
- Preventive anti-aging benefits
- Foundation for long-term skin health
Real patient review: "I did 3 Rejuran sessions, one month apart. By month 2-3, my skin quality was completely different—smoother, bouncier, healthier. Even my dermatologist was impressed!"
Duration of Results
Single Session:
- Immediate effects: 1-2 weeks
- Skin quality improvement: 2-3 months
Treatment Series (3-4 sessions):
- Cumulative regeneration: Results last 6-12 months
- Some patients report benefits lasting up to 18 months
- Each treatment builds on previous foundation
Maintenance Strategy:
- Annual or bi-annual treatment series
- Quarterly single sessions
- Combination with other treatments
Expected Improvement Percentages
Based on Korean patient reviews and clinic data:
- Skin texture: 60-80% improvement
- Fine lines: 40-60% reduction
- Skin elasticity: 50-70% improvement
- Redness/inflammation: 70-90% reduction
- Overall skin quality: 70-85% of patients report significant satisfaction
- Pore size: 30-50% reduction
The Rejuran Treatment Experience
What Happens During Your Appointment
Step 1: Consultation (15-30 minutes)
- Skin assessment and concern discussion
- Determination of appropriate Rejuran type
- Amount recommendation (2cc, 3cc, 4cc)
- Pricing and package options
Step 2: Cleansing (5 minutes) Thorough facial cleansing to remove all impurities.
Step 3: Numbing Cream (20-30 minutes)
- Topical anesthetic applied to entire face
- Essential for comfort (Rejuran involves many injections)
- Korean clinics use high-quality numbing products
Step 4: Rejuran Injection (15-30 minutes)
Traditional Hand Injection (most common):
- Nappage technique: Multiple shallow injections across entire face
- 50-100+ injection points depending on coverage
- Each injection deposits small amount of product
- Creates even distribution across treatment area
Injection Gun Method (newer, more comfortable):
- Automated multi-needle device
- Faster treatment time
- More even product distribution
- Less painful than hand injection
- Costs ₩20,000-50,000 more
What It Feels Like:
- With numbing: 4-5/10 (multiple pinpricks, tolerable)
- Without numbing: 7-8/10 (not recommended)
- More injections = more cumulative discomfort
- Bony areas (forehead, jawline) more sensitive
Step 5: Massage and Cooling (5-10 minutes)
- Gentle massage to distribute product evenly
- Cooling mask to reduce redness and swelling
- Soothing serum application
Step 6: Post-Treatment Care (5 minutes)
- Moisturizer and SPF application
- Aftercare instructions
- Photography (optional)
Total Appointment Time: 60-90 minutes
Pain and Discomfort Level
Pain Rating: Most patients rate Rejuran 5-6/10 with numbing
Why More Uncomfortable Than Other Boosters:
- Many more injection points (50-100 vs. 20-40 for other treatments)
- Cumulative discomfort from multiple pricks
- PDRN has thicker viscosity than pure HA
- Some formulations can sting slightly
Comparison:
- More painful than: Aqua skin boosters, simple HA injections
- About same as: Juvelook, some mesotherapy treatments
- Less painful than: Microneedling RF, aggressive laser treatments
Korean Comfort Solutions:
- Premium numbing creams
- Injection gun for faster, more comfortable treatment
- "Sleep Rejuran" (under sedation) for extremely sensitive patients
- Ice packs before and after
- Distraction techniques
Side Effects and Recovery
Rejuran is considered very safe with minimal serious side effects when properly administered.
Common, Expected Side Effects
Immediately After (0-24 hours):
- Multiple small bumps (papules) at each injection site (completely normal)
- Redness: Moderate, fades within 4-24 hours
- Swelling: Mild to moderate, peaks at 12-24 hours
- Tenderness: Skin feels sensitive to touch
- Warmth: Treated areas feel warm
Days 2-7:
- Bumps flatten within 1-3 days as product distributes
- Possible bruising: 20-30% of patients experience minor bruising
- Tightness: Skin may feel firm as healing begins
- Dryness: Temporary, improves with moisturizer
These are normal healing responses and indicate the treatment is working.
Less Common Side Effects
- Prolonged swelling: Lasting 3-7 days (rare)
- Visible lumps: If product doesn't distribute evenly (massage helps)
- Increased sensitivity: Heightened reaction to skincare products temporarily
- Temporary redness: Lasting several days in very sensitive skin
- Itching: As healing progresses (don't scratch!)
Rare but Possible Complications
- Infection: Extremely rare with proper sterile technique
- Allergic reaction: Very rare (PDRN is highly biocompatible)
- Vascular complications: Extremely rare with experienced injectors
- Granuloma formation: Very rare delayed reaction
- Persistent bumps: May require hyaluronidase (for HB version) or time to resolve
Who Should Avoid Rejuran?
❌ Absolute Contraindications:
- Pregnancy or breastfeeding
- Active skin infection or inflammation
- Allergy to salmon or seafood (PDRN is salmon-derived!)
- Open wounds in treatment area
- History of severe allergic reactions to injectables
❌ Relative Contraindications (Consult Doctor):
- Autoimmune disorders
- Immunosuppressive medications
- Recent facial surgery (wait 3-6 months)
- Active severe acne
- Blood clotting disorders
- History of keloid scarring
Important: If you have a seafood allergy, inform your doctor. While PDRN is highly purified, caution is warranted.
Post-Treatment Care: Maximizing Results
Proper aftercare optimizes healing and results.
First 24-48 Hours: Critical Window
DO:
- ✅ Apply ice packs (10-15 minutes every 2-3 hours) for swelling
- ✅ Sleep with head elevated (reduces swelling)
- ✅ Drink plenty of water (supports healing)
- ✅ Use gentle, fragrance-free cleanser
- ✅ Apply prescribed soothing cream
- ✅ Take arnica supplements (reduces bruising)
DON'T:
- ❌ Touch, rub, or massage treated areas (first 6 hours)
- ❌ Apply makeup for 12-24 hours
- ❌ Use hot water on face
- ❌ Exercise or activities causing sweating (24-48 hours)
- ❌ Consume alcohol (increases swelling and bruising)
- ❌ Sleep face-down (can affect product distribution)
First Week Care
Skincare Routine:
- Gentle cleanser (lukewarm water only)
- Hydrating toner/essence
- Moisturizer (ceramide-rich recommended)
- SPF 50+ sunscreen (critical!)
Activities to Avoid:
- ❌ Vigorous exercise (wait 48-72 hours)
- ❌ Saunas, steam rooms, hot baths (wait 1 week)
- ❌ Facial massage (wait 1 week)
- ❌ Other facial treatments (lasers, peels, microneedling) - wait 2-4 weeks
- ❌ Dental work (wait 1-2 weeks)
- ❌ Strong acids, retinol (wait 3-5 days)
Ongoing Care (Weeks 2-4 and Beyond)
Support Skin Healing:
- Gentle skincare: No harsh exfoliants or aggressive treatments
- Hydration: 2-3 liters water daily
- Sun protection: UV damage undoes healing (SPF 50+ daily)
- Adequate sleep: 7-9 hours for cellular repair
- Healthy diet: Antioxidants, vitamins, protein
- No smoking: Destroys collagen and impairs healing
Enhance Results:
- Vitamin C serum (after 1 week): Supports collagen production
- Peptide products: Enhance skin repair
- Sheet masks: Popular in Korea, maintain hydration
- Quality moisturizer: Support barrier function
Between Treatment Sessions
If doing a series (recommended):
- Schedule 2-4 weeks apart for optimal cumulative effect
- Maintain consistent gentle skincare
- Avoid sun damage between sessions
- Track progress with photos (same lighting)
- Communicate any concerns to your doctor
Rejuran vs. Other Skin Treatments
Understanding how Rejuran compares helps you choose the right treatment.
Rejuran vs. Juvelook
| Feature | Rejuran | Juvelook |
|---|---|---|
| Main Ingredient | PDRN (Polynucleotide) | PDLA + Hyaluronic Acid |
| Primary Action | Skin healing & regeneration | Collagen stimulation + hydration |
| Best For | Damaged, sensitive, inflamed skin | Pores, texture, volume |
| Mechanism | DNA-level cellular repair | Collagen building |
| Immediate Glow | Moderate | Strong (HA component) |
| Results Timeline | 1-4 weeks | 4-12 weeks |
| Duration | 6-12 months | 9-12 months |
| Pain Level | 5-6/10 (many injections) | 3-4/10 (fewer injections) |
| Price (Korea) | $115-$169/session | $192-$308/session |
Choose Rejuran if: You have sensitive, damaged, or inflamed skin needing healing Choose Juvelook if: You want pore refinement and structural improvement
Rejuran vs. Aqua Skin Booster
| Feature | Rejuran | Aqua Skin Booster |
|---|---|---|
| Technology | PDRN (DNA healing) | HA + vitamins + peptides |
| Primary Goal | Skin healing & anti-aging | Hydration & glow |
| Depth of Action | Cellular level (DNA) | Surface to mid-dermis |
| Best For | Skin repair, inflammation | Immediate glow, hydration |
| Durability | 6-12 months | 3-6 months |
| Sessions Needed | 3-4 recommended | 1-3 sufficient for glow |
| Price | Higher | Lower |
Choose Rejuran if: You want fundamental skin healing and long-term improvement Choose Aqua Booster if: You want quick hydration and glass skin effect
Rejuran vs. PRP (Platelet-Rich Plasma)
| Feature | Rejuran (PDRN) | PRP (Vampire Facial) |
|---|---|---|
| Source | Salmon DNA (standardized) | Your own blood |
| Consistency | Standardized potency | Variable (depends on your blood quality) |
| Procedure | Direct injection | Blood draw + processing + injection |
| Time Required | 60-90 minutes | 90-120 minutes |
| Downtime | Mild (bumps, redness) | Moderate (more intense redness) |
| Results | Predictable, consistent | Variable by individual |
| Price (Korea) | $115-$169 | $200-$400 |
Choose Rejuran if: You want standardized, predictable results Choose PRP if: You prefer autologous (own tissue) treatments
Real Patient Reviews from Korea
Highly Satisfied Patients
"I did 4 Rejuran Healer sessions for my sensitive, irritated skin. After years of redness and inflammation, my skin finally calmed down. It's now smooth, bouncy, and healthy-looking. Life-changing treatment!"
"At 52, my skin was thin, dull, and tired. Three Rejuran HB sessions later, I have this youthful glow and plumpness I haven't seen in years. Friends think I've had a facelift!"
"Rejuran Eye completely transformed my under-eye area. The fine lines are so much softer, dark circles improved, and the skin looks healthier. Worth every won!"
Moderately Satisfied
"Rejuran definitely improved my skin texture and reduced my redness. Results were good but gradual—I needed to be patient. Not the dramatic overnight change I hoped for, but solid long-term improvement."
"Did 3 sessions and my skin is nicer—smoother, more hydrated, healthier. But the improvement is subtle. I think my expectations were too high based on Instagram before/afters."
"The treatment helped with my acne scars and improved my skin quality overall. Results are good but required multiple sessions and maintenance. It's more of a long-term investment than a quick fix."
Mixed or Disappointed
"Spent ₩500,000 on 3 sessions and honestly can't see much difference. My skin feels slightly better, but no visible improvement in my concerns. Maybe PDRN just doesn't work for everyone."
"The injections were really uncomfortable—so many tiny pricks. Results were okay but not worth the pain and cost for me. I got better results from lasers."
"Had an allergic reaction (I have seafood allergies, which I didn't connect to salmon-derived PDRN). Developed itching and bumps that lasted 2 weeks. My fault for not mentioning my allergies!"
Common Themes in Reviews
- Patience essential: Results are gradual, not immediate
- Best for sensitive/damaged skin: Dramatic improvement for compromised skin
- Multiple sessions crucial: 1 session gives minimal lasting results
- Discomfort factor: Many injections = more uncomfortable than some treatments
- Healing focus: Different from volumizing or dramatic lifting
- Korean clinics most experienced: Treatment originated in Korea
Choosing the Right Clinic in Seoul
Red Flags to Avoid
❌ Extremely Low Prices: Authentic Rejuran under ₩100,000 ($77) is suspicious
❌ Can't Verify Product: Genuine Rejuran has specific packaging from Pharma Research
❌ No Patch Test Offered: Important for those with sensitive skin or allergies
❌ Vague "PDRN Treatment" Claims: Verify it's genuine Rejuran, not generic PDRN
❌ No Consultation: Reputable clinics assess suitability first
❌ Pressure Tactics: Forcing large package purchases immediately
What to Look For
✅ Authentic Rejuran: Verify product packaging (made by Pharma Research Co.)
✅ Experienced Injector: Board-certified dermatologist preferred
✅ Customized Treatment: Type and amount tailored to your concerns
✅ Realistic Expectations: Honest about gradual results timeline
✅ Before/After Photos: Real patient results from that clinic
✅ English Communication: Essential for discussing concerns
✅ Proper Numbing: Quality anesthetic for comfort
✅ Transparent Pricing: Clear costs with no hidden fees
Best Areas for Rejuran in Seoul
Gangnam (강남):
- Most experienced Rejuran practitioners
- Premium service and expertise
- Price: ₩200,000-₩320,000/session ($154-$247)
- Best for: Complex cases, maximum expertise
Apgujeong (압구정):
- High-quality clinics
- Celebrity clientele
- Price: ₩170,000-₩280,000/session ($131-$215)
- Best for: Quality + competitive pricing
Sinsa-dong (신사동):
- Modern boutique clinics
- Mid-range pricing
- Price: ₩150,000-₩240,000/session ($115-$185)
- Best for: Good value
Myeongdong (명동):
- Tourist-friendly
- English support common
- Price: ₩130,000-₩220,000/session ($100-$169)
- Best for: Convenient access
Hongdae (홍대):
- Budget-friendly options
- Younger crowd
- Price: ₩100,000-₩180,000/session ($77-$138)
- Best for: Value seekers
Questions to Ask During Consultation
- Is this authentic Rejuran? (Ask to see the packaging)
- Which Rejuran type do you recommend for my concerns?
- How much product (cc) do I need?
- How many sessions do you recommend?
- Do you use hand injection or injection gun?
- What are the risks for my skin type?
- I have seafood allergies—is Rejuran safe for me?
- What's included in the price?
- Can I see before/after photos of similar cases?
- What's your protocol if complications occur?
Tips for International Visitors
Planning Your Rejuran Trip to Seoul
Timeline Considerations:
- Minimum stay: 1 week (allows for 1-2 treatments)
- Ideal stay: 3-4 weeks (allows 2-3 treatments spaced properly)
- Alternative: Get 1-2 treatments during visit, continue at home if available
Scheduling Strategy:
- Contact clinics 2-3 weeks ahead
- Confirm authentic Rejuran and pricing
- Schedule first treatment early in trip
- Avoid important events within 2-3 days (bumps and swelling)
- Space sessions 2-4 weeks apart if doing multiple
What to Bring
- Passport or ID
- Cash and credit cards (cash discounts common)
- List of allergies (especially seafood!)
- Current medications list
- Photos showing concerns
- Comfortable mask (for covering bumps when leaving)
Post-Treatment Travel
Flying After Rejuran:
- Safe to fly after initial swelling subsides (24-48 hours)
- Bumps may still be visible but not painful
- Stay hydrated during flight
- Avoid alcohol on plane
- Continue gentle skincare
Managing Side Effects While Traveling:
- Ice packs or hotel ice for swelling
- Arnica gel and supplements
- Gentle, fragrance-free skincare products
- Mineral makeup to cover bumps (after 24 hours)
- Plan indoor activities for first 2-3 days
Frequently Asked Questions
Q: Does Rejuran hurt? A: With numbing cream, most patients rate it 5-6/10—tolerable but noticeable due to many injection points. The injection gun method is more comfortable than traditional hand injection.
Q: How many treatments do I need? A: Korean dermatologists typically recommend 3-4 sessions spaced 2-4 weeks apart for optimal cumulative healing. Mild concerns may improve with 2 sessions; damaged or mature skin benefits from 4-5 treatments.
Q: When will I see results? A: 59% of patients notice effects immediately (hydration, glow). Gradual healing improvements appear over 2-4 weeks, with maximum results at 2-3 months as cellular regeneration completes.
Q: Is Rejuran safe if I have seafood allergies? A: Inform your doctor about seafood allergies. While PDRN is highly purified and most seafood-allergic patients tolerate it well, caution is appropriate. A patch test may be recommended.
Q: Rejuran or Juvelook—which is better? A: Different purposes. Rejuran: Best for skin healing, reducing inflammation, repairing damage. Juvelook: Best for pore refinement, structural improvement, volumizing. Rejuran focuses on healing; Juvelook on building.
Q: Can Rejuran treat acne scars? A: Yes! Rejuran S (Scar formula) is specifically designed for acne scar treatment. Regular Rejuran Healer also improves mild scarring. Expect 30-50% improvement over 3-4 sessions for mild to moderate scars.
Q: What's the difference between Rejuran Healer and HB? A: Rejuran HB adds hyaluronic acid for immediate hydration and glow. Healer is pure PDRN focused on healing. HB provides instant glass skin effect plus long-term healing; Healer is gradual improvement only.
Q: How long do results last? A: With a series of 3-4 treatments, results typically last 6-12 months, sometimes up to 18 months. Annual or bi-annual maintenance sessions help sustain benefits.
Q: Can I combine Rejuran with other treatments? A: Yes! Commonly combined with lasers, Botox, fillers, and other skin boosters. Your doctor will advise on timing—some can be done same day, others need 2-4 weeks spacing.
Q: Will the bumps be visible? A: Yes, multiple small bumps will be visible for 12-48 hours after treatment. They're very noticeable immediately after but flatten significantly within 24 hours. Plan accordingly for social events.
Is Rejuran Worth It? Final Verdict
Rejuran represents a fundamentally different approach to skin improvement—working at the DNA level to heal and regenerate rather than simply plumping or stimulating. For the right candidate, it offers genuine, lasting skin quality improvement.
Rejuran is Worth It If:
✅ You have damaged, sensitive, or inflamed skin needing healing ✅ You prefer biological, regenerative treatments ✅ You can commit to 3-4 treatment sessions for cumulative results ✅ You're patient with gradual improvement over weeks ✅ You value long-term skin health over quick fixes ✅ You want to address underlying skin quality, not just surface issues ✅ You're seeking preventive anti-aging treatment ✅ You can tolerate multiple injections and temporary bumps
Consider Alternatives If:
❌ You have severe seafood allergies (consult doctor first) ❌ You want immediate, dramatic volumizing (fillers better) ❌ You need quick results for an upcoming event ❌ You can't tolerate many injections ❌ Your budget is very limited (single sessions give minimal lasting results) ❌ You want primarily hydration (simpler boosters cheaper) ❌ You're looking for dramatic lifting (consider Ulthera or threads)
Conclusion
Rejuran has revolutionized Korean skincare by introducing PDRN-based cellular healing to aesthetic medicine. As one of the first and most researched salmon DNA treatments, Rejuran offers scientifically-backed skin regeneration that goes beyond surface-level improvements.
Korea remains the ideal destination for Rejuran treatment—it was developed here, Korean dermatologists have the most experience administering it, and prices are 75-85% lower than Western countries. The variety of Rejuran formulations (Healer, HB, Eye, Scar, Tone-up) allows for customized treatment addressing specific concerns.
The key to Rejuran success lies in choosing an experienced clinic with authentic products, completing a full treatment series (3-4 sessions), setting realistic expectations about gradual results, and supporting healing through proper skincare and lifestyle. While the multiple injections can be uncomfortable and initial bumps are visible, the majority of Korean patients report high satisfaction with natural, lasting skin quality improvement.
Ready to heal and rejuvenate your skin at the cellular level? Research clinics thoroughly, verify authentic Rejuran products, discuss your allergies and concerns openly, and prepare for a gradual but genuine transformation in your skin's health and vitality.
⚠️ Medical Disclaimer: This article provides general information about Rejuran PDRN skin booster treatment in Korea. It is not intended as medical advice. Results vary significantly based on individual factors including age, skin condition, lifestyle, and natural healing capacity. Rejuran carries risks including allergic reactions (especially in those with seafood allergies), swelling, bruising, infection, and other complications. Not all patients are suitable candidates, and results are not guaranteed. PDRN is derived from salmon—inform your doctor of any seafood or fish allergies. Always consult with a board-certified dermatologist before undergoing any cosmetic procedure. Discuss your complete medical history, allergies, medications, expectations, and concerns during your consultation.
Last Updated: November 22, 2025 Reading Time: 19 minutes
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