PRP Vampire Facial in Korea: Complete Skin Regeneration Guide 2025

Looking for natural, science-backed skin rejuvenation? PRP (Platelet-Rich Plasma) treatment—popularly known as the "vampire facial"—uses your own blood's healing power to regenerate skin, boost collagen, and restore a youthful glow. Beloved by celebrities and backed by medical research, PRP has become one of Korea's most sought-after regenerative treatments.

This comprehensive guide explains how PRP works, what to expect, pricing in Korea, how it compares to Rejuran and other skin boosters, who should try it, and everything international visitors need to know.

What is PRP (Vampire Facial)?

PRP stands for Platelet-Rich Plasma—a concentrated portion of your own blood containing high levels of platelets, growth factors, and regenerative proteins. In Korean, it's called 자가혈 주사 (jagahyeol jusa, literally "autologous blood injection").

The Science Behind PRP

What makes it work:

• Platelets: Tiny blood cells packed with growth factors that trigger healing
• Growth factors: Include PDGF, TGF-β, VEGF, EGF—proteins that stimulate cell regeneration
• Stem cell activation: Growth factors wake up dormant skin cells
• Collagen synthesis: Signals fibroblasts to produce new collagen
• Anti-inflammatory proteins: Calm inflammation and promote healing
• No foreign substances: 100% your own biology, minimizing rejection risk

The regeneration process:

1. Blood draw: 10-20ml of your blood (like a standard blood test)
2. Centrifugation: Spun at high speed to separate plasma layers
3. PRP extraction: Concentrated platelet layer isolated (3-8x normal concentration)
4. Activation (optional): Some clinics activate platelets to release growth factors immediately
5. Injection: PRP injected into skin's dermal layer
6. Regeneration: Growth factors trigger collagen production, cell turnover, and tissue repair

Why "Vampire Facial"?

The nickname comes from:

• Drawing your own blood for the treatment
• The blood-red appearance of the concentrated plasma
• Celebrity endorsements (Kim Kardashian famously shared post-treatment photos)

Note: In Korea, PRP is typically injected via micro-injections or microneedling, not applied topically after aggressive needling (the controversial method that made headlines for hygiene issues in unlicensed US facilities).

How PRP Rejuvenates Skin

Mechanisms of Action

Collagen stimulation:

• Growth factors signal fibroblasts to produce Types I and III collagen
• New collagen fibers form over 4-12 weeks
• Skin becomes firmer, plumper, and more elastic

Cell regeneration:

• Stem cells in skin activate and multiply
• Old, damaged cells replaced with healthy new cells
• Improved cell turnover rate

Angiogenesis (new blood vessel formation):

• VEGF (vascular endothelial growth factor) promotes capillary growth
• Better blood flow delivers more nutrients and oxygen
• Healthier, more radiant complexion

Anti-inflammatory effects:

• Anti-inflammatory proteins calm irritated skin
• Reduces redness and sensitivity
• Accelerates healing

Expected Benefits

Skin quality improvements:

• ✅ Fine lines and wrinkles reduction (especially around eyes, mouth)
• ✅ Improved skin texture and smoothness
• ✅ Enhanced firmness and elasticity
• ✅ Reduced pore size
• ✅ Brighter, more radiant complexion
• ✅ Even skin tone
• ✅ Natural glow ("glass skin" effect)
• ✅ Better hydration retention

Specific conditions PRP addresses:

• ✅ Early signs of aging (30s-40s)
• ✅ Sun-damaged skin
• ✅ Acne scars and post-inflammatory marks
• ✅ Stretch marks
• ✅ Dark circles under eyes
• ✅ Sensitive, reactive skin
• ✅ Rosacea and redness
• ✅ Atopic dermatitis (as supportive therapy)
• ✅ Post-laser or post-procedure healing

What PRP cannot fix:

• ❌ Severe wrinkles (needs fillers or Botox)
• ❌ Significant sagging (needs RF lifting or threads)
• ❌ Deep acne scars (needs laser resurfacing)
• ❌ Active acne outbreaks (treat infection first)
• ❌ Pigmentation issues (needs laser or chemical peels)
• ❌ Volume loss (needs dermal fillers)

PRP excels at overall skin quality and regeneration—think of it as upgrading your skin's foundation rather than architectural restructuring.

The PRP Treatment Process

Before Treatment

Consultation:

• Medical history review (blood disorders, medications)
• Skin assessment and treatment goals
• Discussion of realistic expectations
• Explanation of process
• Blood test (some clinics require CBC to verify platelet count)

Preparation:

• Hydrate well: Drink plenty of water 24 hours before
• Eat normally: Don't come on empty stomach (prevents dizziness)
• Avoid blood thinners: Stop aspirin, ibuprofen, fish oil, vitamin E 3-5 days before (consult doctor)
• No alcohol: 24 hours before (thins blood)
• Clean face: Remove all makeup and skincare products

During Treatment (45-75 minutes)

Step 1: Blood Draw (5 minutes)

• 10-20ml blood drawn from arm (standard venipuncture)
• Similar to routine blood test
• Minimal discomfort

Step 2: Centrifugation (10-15 minutes)

• Blood placed in centrifuge machine
• Spun at 3000-4000 RPM for 8-15 minutes
• Separates into three layers:
  • Top: Platelet-poor plasma (PPP)
  • Middle: Platelet-rich plasma (PRP) ← This is extracted
  • Bottom: Red blood cells

Step 3: PRP Preparation (5 minutes)

• PRP layer carefully extracted via syringe
• May be mixed with small amount of calcium chloride or collagen activator
• Prepared in sterile environment

Step 4: Face Preparation (10 minutes)

• Numbing cream applied (if micro-injections used)
• Face cleansed and disinfected
• Treatment area marked

Step 5: Application Method (20-30 minutes)

Option A: Micro-injections (더마톡신 방식)

• Multiple small injections across treatment area
• Delivered into mid-dermis (shallow depth)
• Spacing: Every 1-2cm
• Pain level: 3-5/10 (with numbing cream)
• More precise delivery, better for targeted concerns

Option B: Microneedling + PRP (물광 + PRP)

• Microneedling device creates micro-channels
• PRP applied and massaged in during needling
• Channels allow deeper penetration
• Pain level: 2-4/10 (with numbing cream)
• Better coverage, combines benefits of microneedling

Option C: Laser + PRP (프락셔널 + PRP)

• Fractional laser creates micro-wounds
• PRP applied immediately after
• Enhanced absorption through laser channels
• Pain level: 5-7/10
• Maximum regeneration, addresses scars/texture

After Treatment

Immediate effects (0-24 hours):

• Redness (moderate to significant)
• Swelling (mild to moderate, especially if microneedling used)
• Small bumps at injection sites (if micro-injections)
• Slight bruising possible (10-20% of patients)
• Skin feels warm and tight
• Can look worse before better: Expect 1-3 days of social downtime

Recovery timeline:

• Day 1: Peak redness and swelling
• Day 2-3: Redness fades to pinkness, swelling subsides
• Day 4-7: Back to normal appearance
• Week 2-4: Skin starts looking smoother, brighter
• Week 4-8: Collagen production ramps up, noticeable improvement
• Week 8-12: Peak results achieved

Downtime:

• Social downtime: 1-3 days
• Makeup: Can apply after 24 hours
• Work: Most return next day
• Exercise: Avoid 24-48 hours

PRP vs Other Skin Boosters

Korea offers many skin regeneration treatments. Here's how PRP compares.

PRP vs Rejuran

Bottom line: PRP is more natural (your own blood), less painful, and cheaper per session but requires more frequent maintenance. Rejuran lasts longer and is better for deep hydration and elasticity. Many patients alternate or combine both.

PRP vs Juvelook (쥬베룩)

Bottom line: Juvelook provides longer-lasting volumizing effects, while PRP focuses on quality and regeneration. Juvelook better for deeper wrinkles and volume loss; PRP better for overall skin health.

PRP vs Skin Botox (스킨보톡스)

Bottom line: Different purposes. PRP rebuilds, Skin Botox controls oil and refines pores. Can be combined for comprehensive skin quality improvement.

Comparison Summary

Pricing in Korea (2025)

PRP treatment costs vary widely based on volume, clinic, and whether it's combined with other procedures.

By Treatment Type

PRP Injection Only:

• Basic (1cc): ₩30,000-100,000 ($24-$77)
• Standard (2-3cc): ₩100,000-250,000 ($77-$192)
• Full face (4-5cc): ₩200,000-440,000 ($154-$338)
• Average: ₩150,000 ($115) per session

PRP + Microneedling (MTS/Dermapen):

• Range: ₩200,000-400,000 ($154-$308)
• Average: ₩300,000 ($231)

PRP + Fractional Laser:

• Range: ₩400,000-700,000 ($308-$538)
• Average: ₩500,000 ($385)

PRP for Acne Scars:

• Range: ₩250,000-500,000 ($192-$385)
• Typically combined with CO2 laser or subcision

PRP for Hair Loss (Scalp):

• Range: ₩200,000-400,000 ($154-$308) per session
• Requires 3-6 sessions

Package Deals

3-session packages (most common recommendation):

• PRP only: ₩300,000-900,000 ($231-$692)
• PRP + Microneedling: ₩600,000-1,200,000 ($462-$923)

5-session packages:

• PRP only: ₩500,000-1,500,000 ($385-$1,155)

Factors Affecting Price

Higher prices indicate:

• ✅ Higher PRP concentration and volume
• ✅ Advanced centrifuge equipment
• ✅ Platelet activation devices (52% improved efficacy per 2025 research)
• ✅ Board-certified dermatologist performing treatment
• ✅ Premium clinic location (Gangnam, Cheongdam)
• ✅ Combination with other treatments
• ✅ Sterile single-use kits

Lower prices may indicate:

• ⚠️ Lower PRP volume or concentration
• ⚠️ Nurses performing injections
• ⚠️ Basic equipment without activation devices
• ⚠️ First-time patient promotions

International Price Comparison

Exchange rate: ₩1,300 ≈ $1 USD (November 2025)

Korea offers exceptional value for PRP treatments—even premium packages cost less than single sessions abroad.

Treatment Frequency and Maintenance

Recommended Protocol

Initial series (skin quality improvement):

• 3-5 sessions spaced 3-4 weeks apart
• Builds cumulative collagen and regeneration
• Best results after completing full series

Maintenance (sustaining results):

• Every 3-6 months after initial series
• Younger patients (20s-30s): Every 6 months
• Older patients (40s+): Every 3-4 months

Intensive protocols (acne scars, severe damage):

• 5-8 sessions monthly
• Combined with laser or subcision
• Follow-up maintenance every 2-3 months

By Age and Goal

20s (Prevention):

• 2-3 sessions per year
• Maintain skin quality and prevent early aging
• Lower volume PRP (2-3cc)

30s (Early Intervention):

• 3-4 sessions per year
• Address first signs of aging, texture issues
• Standard volume (3-4cc)

40s-50s (Active Rejuvenation):

• 4-6 sessions per year
• Combat visible aging, loss of elasticity
• Higher volume (4-5cc)
• Consider combining with Rejuran or Juvelook

60s+ (Intensive Repair):

• 6+ sessions per year
• Maximum regeneration support
• Combine with other treatments (Thermage, Ulthera, fillers)

Side Effects and Safety

Common (Expected)

Normal reactions:

• Redness (moderate, 1-3 days)
• Swelling (mild to moderate, 1-3 days)
• Bruising at injection sites (10-20% of patients, 5-7 days)
• Small bumps (if micro-injections, resolve in 1-2 days)
• Warmth and tightness (first 24 hours)
• Mild tenderness (2-3 days)

These are normal inflammatory responses showing the treatment is working.

Rare Complications

Uncommon issues:

• Infection (extremely rare with proper sterile technique)
• Allergic reaction (very rare since it's your own blood)
• Excessive bruising (more common in patients on blood thinners)
• Prolonged swelling (>1 week)
• Skin irregularities (temporary)
• No improvement (poor PRP quality or insufficient sessions)

Controversial 2019 incident: In the US, an unlicensed spa caused HIV and Hepatitis B infections through contaminated equipment. This cannot happen at licensed Korean medical clinics which follow strict sterilization protocols and use single-use sterile kits.

Who Should Avoid PRP

Contraindications:

• ❌ Pregnant or breastfeeding
• ❌ Active skin infection or open wounds
• ❌ Blood disorders (low platelet count, clotting disorders, anemia)
• ❌ Taking anticoagulants (warfarin, heparin—consult doctor)
• ❌ Cancer (especially blood cancers)
• ❌ Immunosuppressive therapy
• ❌ Active acne outbreak (mild acne okay)
• ❌ Autoimmune conditions (discuss with doctor)

Relative contraindications (discuss with doctor):

• Chronic liver disease
• Diabetes (may affect healing)
• Smokers (reduces effectiveness)
• Recent steroid injections

Top PRP Clinics in Seoul

Recommended Clinics

1. Sinsain Dermatology (신사인피부과)

• Location: Multiple Gangnam locations
• Specialties: Skin regeneration, customized PRP protocols
• Price: ₩150,000-400,000 ($115-$308)
• English support: Yes
• Why choose: Experienced with international patients, advanced PRP technology

2. Bluebird Skin Clinic (파랑새피부과)

• Location: Bundang, Seohyun
• Specialties: PRP combined with other skin boosters
• Price: ₩200,000-350,000 ($154-$270)
• Why choose: Detailed comparison and consultation, scientific approach

3. Yeoshin Plastic Surgery (여신성형외과)

• Location: Gangnam
• Specialties: PRP facial rejuvenation, scar treatment
• Price: ₩100,000-300,000 ($77-$231)
• Promotions: Frequent discount events
• Why choose: Affordable without compromising quality

4. Mein Clinic

• Location: Seoul (multiple locations)
• Specialties: "Ultimate regeneration" PRP protocols
• Price: ₩200,000-440,000 ($154-$338)
• Why choose: Advanced platelet activation technology

What to Verify Before Booking

Essential checks:

• ✅ Licensed medical facility (not a spa or salon)
• ✅ Board-certified dermatologist or plastic surgeon
• ✅ Sterile, single-use PRP kits
• ✅ Medical-grade centrifuge equipment
• ✅ Clear pricing (PRP volume, concentration specified)
• ✅ Consultation to assess candidacy
• ✅ Before/after photos
• ✅ English support if needed

Red flags:

• ❌ Non-medical establishments offering PRP
• ❌ Reusable equipment (must be single-use sterile kits)
• ❌ Prices too cheap (<₩50,000 for full face—suspiciously low)
• ❌ No doctor consultation
• ❌ Pressure to buy large packages upfront
• ❌ Unable to explain PRP preparation process

Post-Treatment Care

First 24-48 Hours

DO:

• ✅ Keep face clean with gentle cleanser
• ✅ Apply healing ointment if provided by clinic
• ✅ Stay hydrated (supports healing)
• ✅ Sleep with head elevated (reduces swelling)
• ✅ Apply cool compresses (not ice directly on skin)
• ✅ Take Arnica supplements (reduces bruising)

DON'T:

• ❌ Wash face for first 6-12 hours (let PRP absorb)
• ❌ Apply makeup for 24 hours
• ❌ Touch or massage treated area excessively
• ❌ Exercise or activities that cause sweating
• ❌ Alcohol (increases swelling and bruising)
• ❌ Hot environments (sauna, steam room, hot yoga)
• ❌ Direct sun exposure

Following Weeks

Recommended skincare:

• ✅ Gentle, hydrating products only
• ✅ SPF 50+ daily (crucial for regeneration)
• ✅ Hyaluronic acid serum (supports moisture)
• ✅ Ceramide creams (repair skin barrier)
• ✅ Gentle cleansers (no harsh scrubs)

Avoid for 1-2 weeks:

• ❌ Retinol, acids, exfoliants (let skin heal first)
• ❌ Other facial treatments (microneedling, lasers, peels)
• ❌ Swimming pools (chlorine irritates)
• ❌ Harsh scrubs or brushes
• ❌ Botox or fillers (wait 2 weeks minimum)

Maximizing Results

Support your body's regeneration:

• Nutrition: Protein-rich diet (collagen building blocks)
• Vitamins: Vitamin C (essential for collagen), Zinc (wound healing)
• Hydration: 2+ liters water daily
• Sleep: 7-8 hours (skin repairs at night)
• Avoid smoking: Destroys collagen, impairs healing significantly
• Limit alcohol: Dehydrates skin, impairs regeneration
• Sun protection: UV damages new collagen
• Stress management: Chronic stress impairs healing

Frequently Asked Questions

Q: Does PRP hurt? A: With numbing cream, pain is manageable (3-5/10). Micro-injections feel like tiny pinches. Microneedling causes less sharp pain but more overall discomfort. Most find it much less painful than Rejuran or tattoo removal.

Q: When will I see results? A: Gradual improvement. Skin may look worse for 1-3 days (redness, swelling), then slight improvement at 2-4 weeks as inflammation subsides and new cells emerge. Real collagen production happens weeks 4-12, with best results after completing 3-5 session series.

Q: How long do results last? A: 3-6 months per session. Cumulative benefits build with repeated treatments—after initial 3-5 session series, maintenance every 3-6 months sustains improvements. Younger skin tends to maintain results longer.

Q: Is PRP safe? A: Very safe when performed correctly. Since it's your own blood, allergic reactions are nearly impossible. Main risks are infection (prevented by sterile technique) and bruising. Choose licensed medical facilities with proper sterilization protocols.

Q: Can I combine PRP with other treatments? A: Yes! Popular combinations:

• PRP + Microneedling: Enhanced absorption and regeneration
• PRP + Laser: Maximum collagen stimulation for scars
• PRP + Botox/Fillers: Wait 2 weeks between treatments
• PRP + Rejuran: Alternating sessions for comprehensive skin quality
• PRP + Skin Botox: Regeneration + oil control

Q: How is PRP different from "vampire facial" horror stories? A: The 2019 US incident involved an unlicensed spa using unsterilized equipment and applying PRP topically after deep needling. Korean medical clinics use sterile, single-use equipment, proper sterilization, and inject PRP properly into dermis. When done correctly at medical facilities, PRP is very safe.

Q: Do I need to do anything special before treatment? A: Yes:

• Stay hydrated (drink plenty of water 24 hours before)
• Avoid blood thinners 3-5 days before (aspirin, ibuprofen, fish oil—consult doctor)
• Don't drink alcohol 24 hours before
• Eat normally (don't come on empty stomach)
• Remove all makeup

Q: Can I do PRP if I have sensitive skin? A: Absolutely! PRP is actually ideal for sensitive skin, rosacea, and reactive skin. It's your own blood, so no foreign substances to react to. The growth factors can help calm inflammation and strengthen skin barrier.

Q: What's the difference between cheap and expensive PRP? A: Price differences reflect:

• Volume: 1cc vs 5cc makes huge difference
• Concentration: Higher platelet count = better results
• Equipment: Advanced centrifuges and activation devices improve efficacy by 52%
• Technique: Experienced doctors know optimal injection depth and spacing
• Sterility: Premium clinics use hospital-grade sterile protocols

Very cheap PRP (<₩50,000) may have low volume/concentration or less experienced operators.

Q: Can men get PRP? A: Yes! Very popular for skin quality improvement, scar treatment, and hair loss prevention. Gender doesn't affect efficacy.

Q: What if I'm only visiting Seoul briefly? A: You can do single sessions, but results are better with 3-5 session series. Consider:

• Schedule 2-3 sessions during your visit (spaced 2-3 weeks apart)
• Return for maintenance every 6-12 months
• Single session still provides benefits, just less dramatic than full series

Conclusion

PRP (vampire facial) represents one of the most natural, science-backed approaches to skin rejuvenation—harnessing your own blood's healing power to regenerate tissue, boost collagen, and restore youthful radiance. With minimal downtime, excellent safety profile, and natural-looking results, it's a perfect choice for anyone seeking genuine skin quality improvement.

Is PRP Right for You?

Choose PRP if:

• ✅ You want natural, biological regeneration
• ✅ You have sensitive or reactive skin
• ✅ You're in your 30s-50s with early to moderate aging
• ✅ You want to improve overall skin quality
• ✅ You have acne scars or sun damage
• ✅ Budget-conscious (more affordable than premium treatments)
• ✅ You prefer gradual, natural-looking improvements

Consider alternatives if:

• ❌ You want instant, dramatic results (fillers provide immediate volume)
• ❌ You have severe skin laxity (RF lifting or threads more appropriate)
• ❌ You need longer duration (Juvelook or Rejuran last longer)
• ❌ You can't tolerate any downtime (though PRP downtime is minimal)
• ❌ You have blood disorders or contraindications

Final Verdict

At $24-$338 per session in Korea (compared to $500-$2,000 in Western countries), PRP offers exceptional value for natural skin rejuvenation. The 70-95% savings make completing a full 3-5 session series easily affordable for international medical tourists.

If you're seeking genuine skin quality improvement through your body's own healing mechanisms—not just covering up aging with fillers—PRP vampire facial is one of the smartest investments you can make in your skin.

Ready to try nature's ultimate skin regeneration? Find a reputable Seoul clinic, verify their sterilization protocols, complete an initial 3-5 session series, and experience why PRP has become Korea's go-to treatment for natural, lasting skin rejuvenation.

⚠️ Medical Disclaimer: This article provides general information about PRP treatments. It is not medical advice and should not replace consultation with a qualified healthcare professional. Always consult with a licensed dermatologist or plastic surgeon before undergoing any cosmetic procedure. Results vary based on individual factors including age, skin condition, and lifestyle. All procedures carry potential risks and side effects. Ensure treatments are performed at licensed medical facilities using proper sterilization protocols. The information provided, including pricing and clinic details, is current as of November 2025 and subject to change.

Last Updated: November 6, 2025 Reading Time: 8 minutes