Gouri PCL in Korea: Complete Guide to the World's First Liquid Collagen Stimulator 2025

In the ever-evolving world of Korean aesthetic medicine, a groundbreaking innovation is taking the anti-aging world by storm: Gouri, the world's first fully liquid PCL (Polycaprolactone) collagen stimulator. Developed in Korea and making waves globally, Gouri represents a significant leap forward in bio-stimulator technology, offering a unique approach to natural skin rejuvenation that's changing how we think about anti-aging treatments.

What is Gouri?

Gouri is a revolutionary injectable bio-stimulator that uses liquid-form PCL (Polycaprolactone) to stimulate your body's natural collagen production. Unlike traditional collagen stimulators like Sculptra or Ellanse that use particle suspensions, Gouri is the world's first fully liquid PCL formulation, offering a fundamentally different approach to skin rejuvenation.

The Science Behind Gouri

PCL (Polycaprolactone) is a biocompatible, biodegradable synthetic polymer that has been used safely in medical applications for decades (dissolvable sutures, drug delivery systems, etc.). When injected into the skin:

1. Immediate 3D Scaffold: The liquid PCL forms a three-dimensional scaffold structure immediately upon injection
2. Collagen Activation: Over approximately 24 weeks (6 months), the PCL scaffold triggers your skin's fibroblasts to produce new collagen
3. Gradual Improvement: Skin density, elasticity, and overall quality improve progressively
4. Natural Degradation: PCL gradually breaks down over 12-24 months, leaving behind newly formed collagen
5. Long-lasting Results: Benefits last up to 12 months, with natural-looking enhancement

What Makes Gouri Unique?

Revolutionary Liquid Formulation:

•  100% Liquid: Unlike Sculptra (powder reconstitution) or Ellanse (suspension), Gouri is fully liquid
•  Immediate Integration: Spreads evenly throughout tissue for natural results
•  No Reconstitution: Pre-filled syringe ready to use, ensuring consistency
•  Even Distribution: Liquid form allows for uniform spread across treatment areas
•  Minimal Risk of Nodules: Smooth liquid texture reduces lumping compared to particle-based products

Korean Innovation: Developed by Dexlevo Co., Ltd., a Korean biotechnology company, Gouri represents Korea's leadership in aesthetic innovationalongside their global reputation for K-beauty and advanced skincare treatments.

Benefits and Effects of Gouri

Gouri offers comprehensive anti-aging benefits that develop progressively over months:

Primary Benefits

1. Comprehensive Collagen Stimulation

• Activates natural collagen production throughout treated areas
• Improves overall skin density and structural support
• Creates 3D matrix for long-term skin quality enhancement

2. Skin Elasticity Improvement (� <� �%  )

• Visibly firmer, more resilient skin
• Reduced sagging and improved skin tone
• Enhanced facial contours

3. Fine Line and Wrinkle Reduction

• Softens lines around eyes, mouth, and forehead
• Gradual smoothing of expression lines
• Natural-looking rejuvenation without frozen appearance

4. Skin Texture Enhancement

• Smoother, more refined skin surface
• Improved pore appearance
• Enhanced overall skin quality

5. Skin Tone Evenness (<�� �|)

• More uniform complexion
• Reduced dullness
• Natural radiance and glow

Secondary Benefits

 Pore Reduction: Improved skin structure minimizes enlarged pores  Hydration Boost: Enhanced skin barrier function improves moisture retention  Natural Results: Gradual improvement looks authentic, never overdone  Preventative Anti-Aging: Slows progression of aging signs  Whole-Face Rejuvenation: Unlike targeted fillers, Gouri improves overall skin quality

Results Timeline

Understanding when to expect results helps set realistic expectations:

Week 1: ��� �� � 1�| t�� � (Results visible within 1 week of injection)

• Initial skin tightening
• Subtle improvement in texture
• Enhanced hydration

Weeks 2-4:

• Progressive collagen activation
• Continued texture refinement
• Gradual elasticity improvement

Weeks 6-12:

• Noticeable firmness increase
• Visible reduction in fine lines
• Enhanced skin density

Weeks 12-24 (3-6 months):

• } 24�� x� |� �1 \1T (Collagen production activated over approximately 24 weeks)
• Peak results achieved
• Maximum elasticity and texture improvement
• Significant reduction in wrinkles

6-12 Months:

• ��� \� 1DL� �� (Results last up to one year)
• Maintained benefits
• Gradual, natural-looking enhancement

Gouri Pricing in Korea 2025

As a cutting-edge treatment recently introduced globally, Gouri pricing reflects its innovative technology while remaining competitive with other collagen stimulators.

Estimated Gouri Pricing (Korea)

Per Vial (1ml):

• Standard Clinics: �300,000-�500,000 ($231-$385)
• Premium Clinics: �500,000-�800,000 ($385-$615)
• High-End Clinics: �800,000-�1,200,000 ($615-$923)

Full Treatment Course (3-4 vials):

• Total Investment: �1,200,000-�3,600,000 ($923-$2,769)
• Average Cost: �2,000,000-�2,500,000 ($1,538-$1,923)

Package Deals:

• 3-Session Package: �1,500,000-�2,800,000 ($1,154-$2,154)
• 4-Session Package: �2,000,000-�3,500,000 ($1,538-$2,692)

Note: Pricing information is based on general market estimates as Gouri is a newer treatment. Contact clinics directly for accurate, current pricing. Prices as of November 2025, �1,300 H $1 USD.

Comparison with Other Collagen Stimulators

International Price Comparison

Gouri is still being introduced in international markets, so availability and pricing may vary significantly.

Why Korea for Gouri?

1. Country of Origin: Developed and manufactured in Korea
2. Early Adoption: Korean clinics have the most experience with Gouri
3. Competitive Pricing: Local production and high competition drive value
4. Expertise: Korean dermatologists pioneered techniques for optimal Gouri application
5. Availability: Widely available across Seoul clinics

Gouri vs. Sculptra vs. Ellanse: What's the Difference?

Understanding how Gouri compares to established collagen stimulators helps you make an informed choice.

Key Comparisons

Gouri vs. Sculptra

Material:

• Gouri: Liquid PCL (Polycaprolactone)
• Sculptra: PLLA (Poly-L-Lactic Acid) powder requiring reconstitution

Formulation:

• Gouri: Pre-filled liquid syringe, ready to use
• Sculptra: Powder mixed with water 24-72 hours before injection

Mechanism:

• Gouri: Forms immediate 3D scaffold, gradual collagen stimulation
• Sculptra: Microparticles trigger collagen over time (� � 6� Ā0 �� - effects appear 6 weeks after treatment)

Results Duration:

• Gouri: Up to 12 months
• Sculptra: 18-24 months (\� 2DL� ��)

FDA Approval:

• Gouri: CE marked (Europe), gaining approvals globally
• Sculptra: FDA approved (�m FDA �x� �}� �x)

Nodule Risk:

• Gouri: Lower risk due to liquid formulation
• Sculptra: Higher risk if improperly diluted or massaged (<�� IX� '�' �)

Best For:

• Gouri: Even distribution, whole-face rejuvenation, those wanting newer technology
• Sculptra: Maximum longevity, proven track record, volume restoration

Gouri vs. Ellanse

Material:

• Gouri: 100% liquid PCL
• Ellanse: PCL microspheres suspended in CMC gel carrier

Formulation:

• Gouri: Fully liquid, integrates completely
• Ellanse: Suspension requiring shaking before use

Immediate vs. Progressive:

• Gouri: Progressive collagen stimulation only
• Ellanse: Immediate volume from gel carrier + progressive from PCL

Duration Options:

• Gouri: Single formulation (~12 months)
• Ellanse: Multiple formulations (S: 12 months, M: 18 months, L: 24 months, E: 36+ months)

Application:

• Gouri: Whole-face skin quality improvement
• Ellanse: Targeted volume restoration and contouring

Best For:

• Gouri: Overall skin rejuvenation, natural texture improvement
• Ellanse: Specific volume loss, longer duration needs, immediate + long-term results

Side-by-Side Summary

The Gouri Treatment Process

Knowing what to expect reduces anxiety and ensures you're prepared for treatment.

Before Treatment

Consultation (20-30 minutes):

1. Comprehensive facial assessment
2. Discussion of aging concerns and goals
3. Explanation of Gouri mechanism and realistic expectations
4. Review of medical history
5. Treatment plan customization (number of vials, sessions, areas)
6. Before photos

Recommended Treatment Schedule:

• Initial Course: 3-4 sessions
• Interval: About 1 month between sessions (\ � �<\ 3-4� ĉ ��)
• Maintenance: Every 6-12 months (6�~1D �\ � �� ��)

Preparation Instructions:

• Arrive with clean, makeup-free skin
• Avoid blood thinners (aspirin, ibuprofen, fish oil) 3-5 days before
• Stay well-hydrated
• Avoid alcohol 24 hours before treatment
• Inform doctor of all medications and supplements

During Treatment (30-45 minutes)

Step-by-Step:

1. Cleansing (5 minutes)

   • Thorough cleansing and sanitization
   • Marking treatment areas if needed

2. Numbing (15-20 minutes, optional)

   • Topical anesthetic cream applied
   • Most patients tolerate Gouri well without numbing

3. Injection (15-20 minutes)

   • Multiple small injections across treatment areas
   • Liquid Gouri spreads evenly through tissue
   • Doctor may gently massage to ensure even distribution
   • Common injection points: cheeks, temples, jawline, neck

4. Post-Treatment Care (5 minutes)

   • Ice or cooling pack applied
   • Post-care instructions provided
   • Massage demonstration (if recommended)

Injection Technique

Gouri's liquid formulation allows for different injection approaches:

Common Techniques:

• Micro-Bolus: Multiple small injections spaced across treatment area
• Serial Puncture: Linear injection pattern for even spread
• Cross-Hatching: Grid pattern for comprehensive coverage
• Combination: Tailored approach based on individual needs

Treatment Areas:

• Full face (most common)
• Neck and d�colletage
• Hands
• Targeted zones (temples, cheeks, jawline)

Pain and Discomfort

Pain Level:

• Rating: 2-4 out of 10 (mild to moderate)
• Description: Brief pinching sensation with each injection
• Tolerable: Most patients complete treatment without numbing cream
• Variable: Depends on individual pain tolerance and treatment area

After Treatment

Immediate (0-24 hours):

• Mild redness at injection sites (2-6 hours)
• Slight swelling (can last 1-3 days)
• Possible bruising (3-7 days)
• Minor tenderness to touch
• Small bumps at injection points (resolve within hours)

Days 1-3:

• Swelling subsides
• Bruising may develop or fade
• Can resume normal activities
• Makeup can be applied after 24 hours

Week 1+:

• All visible signs resolve
• Initial skin quality improvements may be noticeable
• Begin to see early results

Downtime:

• Minimal to none
• Most patients return to work same day
• Social activities generally unaffected after 24-48 hours

Side Effects and Safety

Gouri is generally well-tolerated, but understanding potential side effects ensures informed consent and proper expectations.

Common, Expected Side Effects (Temporary)

Normal Reactions:

•  Redness at injection sites (2-6 hours)
•  Swelling (1-3 days)
•  Bruising (3-7 days, varies by individual)
•  Tenderness (2-5 days)
•  Small bumps at injection points (few hours)
•  Minor itching (1-2 days)

These are normal inflammatory responses and resolve without intervention.

Uncommon Side Effects

Less Frequent Issues:

• � Prolonged Swelling: Lasting more than 5 days (5-10% of patients)
• � Significant Bruising: Extensive or long-lasting bruises
• � Asymmetry: Uneven results (usually correctable with touch-up)
• � Delayed Inflammation: Swelling weeks after treatment (rare)

Rare but Serious Complications

Very Rare:

• � Nodules/Granulomas: Firm lumps under skin

  • Gouri Advantage: Lower risk than powder-based stimulators due to liquid formulation
  • Cause: Improper injection technique or individual reaction
  • Treatment: Usually resolves with massage; may require corticosteroid injection

• � Infection: Signs include increasing redness, warmth, pus

  • Prevention: Sterile technique, proper post-care
  • Treatment: Antibiotics if needed

• � Vascular Occlusion: Extremely rare with dermal injections

  • Prevention: Proper injection technique, anatomical knowledge
  • Emergency: Requires immediate treatment

Safety Profile of PCL

PCL is Biocompatible:

• Used in medicine for decades (sutures, implants)
• Fully biodegradable (1-2D� x� � �t - gradually breaks down over 1-2 years)
• Non-allergenic (no pre-testing required)
• Minimal immune reaction

Gouri-Specific Safety Advantages:

•  Pre-filled syringe ensures consistent formulation
•  No reconstitution means no dilution errors
•  Liquid form reduces nodule risk compared to particles
•  Even distribution minimizes lumping

Important Precautions

Before Treatment:

• Disclose all medical conditions and medications
• Avoid supplements that increase bleeding risk (vitamin E, ginkgo, garlic)
• Don't schedule treatment during active skin infections or breakouts
• Avoid if you have autoimmune conditions (discuss with doctor)

After Treatment:

• Don't massage area unless instructed by doctor
• Avoid excessive heat (saunas, hot yoga) for 48 hours
• Sleep elevated first night to minimize swelling
• Avoid intense exercise for 24-48 hours
• No facials, chemical peels, or other treatments for 2 weeks
• Protect from sun exposure with SPF 30+

Who Should Avoid Gouri: L Pregnant or breastfeeding women L Active skin infections or inflammation L Allergies to PCL or components (very rare) L Severe autoimmune disorders (consult specialist first) L History of keloid scarring L Unrealistic expectations about results

Best Candidates for Gouri

Gouri works best for specific age ranges and skin concerns.

Ideal Candidates

Age Range:

• Primary: 30s-50s
• Preventative: Late 20s-30s (early aging signs)
• Corrective: 40s-60s (established aging signs)

Skin Concerns:

• Early to moderate skin laxity
• Loss of skin elasticity and firmness
• Fine lines and wrinkles
• Dull, tired-looking skin
• Uneven skin texture
• Overall skin quality decline
• Preventative anti-aging maintenance

Best Results For:  Those seeking natural, gradual improvement  Patients who want whole-face rejuvenation (not just targeted areas)  People committed to multi-session treatment course  Those willing to wait for progressive results  Candidates wanting collagen stimulation (not immediate volume)  Patients prioritizing skin quality over specific volume restoration

Not Ideal For: L Those needing immediate dramatic results L Severe facial volume loss (may need fillers instead) L Very advanced aging (may need surgery) L Those wanting single-session treatment L Patients seeking targeted wrinkle filling only

Recommended Clinics for Gouri in Seoul

As Gouri is a newer treatment, look for clinics with experience in collagen stimulators and cutting-edge aesthetic technology.

Selection Criteria

When choosing a clinic for Gouri:

•  Experience with collagen stimulators (Sculptra, Ellanse, etc.)
•  Board-certified dermatologists or plastic surgeons
•  Up-to-date with latest aesthetic innovations
•  English-speaking staff for international patients
•  Proper storage and handling of Gouri
•  Realistic expectations setting
•  Comprehensive consultation process

Top Clinic Recommendations

While specific Gouri-focused clinics are still emerging as the treatment gains popularity, the following clinics are known for advanced collagen stimulator treatments and would likely offer Gouri:

1. High-End Aesthetic Dermatology Clinics in Gangnam

• Typically early adopters of new technology
• Premium pricing but excellent expertise
• English support available
• Contact directly to confirm Gouri availability

2. Medical Aesthetic Centers near Gangnam/Apgujeong

• Competitive pricing
• Experience with various collagen stimulators
• Good value for international patients

3. University Hospital Dermatology Departments

• Research-focused approach
• Conservative, evidence-based treatment
• May offer Gouri through clinical programs

Booking Tips

When Contacting Clinics:

1. Confirm Gouri Availability: Not all clinics may stock it yet
2. Ask About Experience: How many Gouri treatments have they performed?
3. Request Pricing: Get detailed quote including number of vials and sessions
4. Verify Authenticity: Ensure they use genuine Gouri from Dexlevo
5. Check Package Deals: Multi-session discounts common
6. Inquire About English Support: Essential for clear communication

Maximizing Your Gouri Results

Getting optimal outcomes from Gouri involves proper preparation, aftercare, and lifestyle factors.

Pre-Treatment Optimization

4-6 Weeks Before:

• Optimize skincare routine with quality products
• Build healthy skin barrier
• Start or maintain good sun protection habits
• Stay well-hydrated
• Consider vitamin C supplements for collagen support

1 Week Before:

• Stop supplements that increase bleeding (vitamin E, fish oil, ginkgo)
• Avoid blood-thinning medications if possible (consult doctor)
• No aggressive exfoliation or treatments
• Ensure skin is healthy (no active breakouts)

Post-Treatment Care

First 24 Hours:

• Apply ice packs intermittently (10 minutes on, 10 off)
• Sleep with head elevated
• Avoid touching or rubbing treated areas
• No makeup for at least 6-12 hours
• Take arnica supplements to reduce bruising (if desired)

First Week:

• Gentle skincare only
• Avoid saunas, steam rooms, hot yoga
• No intense exercise (light walking OK)
• Stay hydrated
• Avoid alcohol (can worsen swelling)

Weeks 2-4:

• Resume normal skincare routine gradually
• Continue sun protection diligently
• Maintain healthy lifestyle habits
• Attend follow-up if scheduled

Lifestyle Factors for Optimal Collagen Production

Essential Habits:

• Sun Protection: SPF 50+ daily (UV damages collagen)
• Protein Intake: 0.8-1g per kg body weight for collagen building blocks
• Vitamin C: Essential for collagen synthesis (citrus, berries, supplements)
• Hydration: 8+ glasses water daily
• Sleep: 7-9 hours for cellular repair and regeneration
• Avoid Smoking: Severely impairs collagen production and degrades existing collagen
• Limit Alcohol: Dehydrates skin and impairs healing
• Manage Stress: Chronic stress accelerates aging

Complementary Treatments

Effective Combinations:

• Gouri + Botox: Collagen stimulation + wrinkle relaxation (space 2 weeks apart)
• Gouri + Hyaluronic Acid Fillers: Skin quality + targeted volume (can combine strategically)
• Gouri + Laser Treatments: Wait 4-6 weeks between treatments
• Gouri + Skin Boosters: Enhanced hydration (can combine same session)
• Gouri + LED Therapy: Promote healing and collagen (safe to combine)

Treatment Timing:

• Same session: Skin boosters, LED therapy
• 2 weeks apart: Botox, light laser treatments
• 4-6 weeks apart: Aggressive laser resurfacing, chemical peels

Maintenance Strategy

Optimal Protocol:

1. Initial Series: 3-4 sessions, 1 month apart
2. Assess Results: Evaluate at 6 months post-final treatment
3. Maintenance: Single session every 6-12 months
4. Long-term: Annual treatments to maintain collagen levels

FAQ About Gouri in Korea

Q: How is Gouri different from regular fillers? A: Gouri is a collagen stimulator, not a filler. Fillers add immediate volume using hyaluronic acid, while Gouri stimulates your body to produce its own collagen over months. Results are more natural and gradual, improving overall skin quality rather than just filling specific areas.

Q: How many Gouri sessions do I need? A: Most patients need 3-4 sessions spaced about 1 month apart for optimal results. Maintenance sessions every 6-12 months help sustain benefits.

Q: When will I see results from Gouri? A: Initial improvements appear within 1 week, but peak results develop over 3-6 months as collagen production ramps up. Patience is essentialthis isn't an instant gratification treatment.

Q: How long do Gouri results last? A: Results typically last up to 12 months. The PCL itself breaks down over 12-24 months, but the collagen it stimulates provides lasting improvement.

Q: Is Gouri painful? A: Most patients rate discomfort at 2-4/10. Brief pinching sensations during injections are tolerable, and numbing cream can be used if needed.

Q: Can Gouri cause lumps or nodules? A: Gouri's liquid formulation significantly reduces this risk compared to powder-based stimulators like Sculptra. Proper injection technique and following post-care instructions further minimize risk.

Q: Is Gouri better than Sculptra? A: "Better" depends on your goals. Gouri offers even distribution and lower nodule risk due to its liquid form, while Sculptra provides longer-lasting results (18-24 months vs. 12 months). Discuss your priorities with your doctor.

Q: Can I combine Gouri with other treatments? A: Yes! Gouri combines well with Botox, fillers, lasers, and skin boosters when properly timed. Discuss your full treatment plan with your provider.

Q: Where can I get Gouri in Korea? A: Gouri is available at advanced aesthetic clinics in Seoul, particularly in Gangnam and Apgujeong. Contact clinics directly to confirm availability, as it's a newer treatment.

Q: How much does Gouri cost in Korea? A: Expect �300,000-�800,000 ($231-$615) per session, with full treatment courses (3-4 sessions) totaling approximately �1,200,000-�3,600,000 ($923-$2,769). Packages typically offer better value.

Q: Is Gouri FDA approved? A: Gouri has CE marking (European approval) and is gaining regulatory approvals worldwide. Check current status for your country, but it's widely available in Korea.

Q: Can men get Gouri? A: Absolutely! Gouri is equally effective for men seeking natural skin rejuvenation and anti-aging benefits.

Q: What if I'm only visiting Korea for a short time? A: You can start your Gouri series during a trip and continue maintenance sessions at home if Gouri is available in your country. Alternatively, consider spacing 2-3 sessions during a 2-month stay.

Conclusion

Gouri represents the cutting edge of Korean aesthetic innovationa testament to Korea's position as a global leader in skincare and anti-aging technology. As the world's first fully liquid PCL collagen stimulator, Gouri offers a unique approach to natural skin rejuvenation that addresses the fundamental cause of aging: collagen loss.

Key Takeaways:

( Revolutionary Technology: Liquid PCL formulation offers advantages over traditional powder-based stimulators

� Gradual, Natural Results: Progressive improvement over 3-6 months looks authentic and enhances overall skin quality

=� Value in Korea: �1,200,000-�3,600,000 ($923-$2,769) for full coursesignificantly less than international pricing

=� Commitment Required: 3-4 sessions plus maintenance for optimal, sustained results

=, Korean Innovation: Developed in Korea with extensive local expertise and competitive pricing

<� Whole-Face Rejuvenation: Unlike targeted fillers, Gouri improves skin quality comprehensively

Is Gouri Right for You?

Gouri is ideal if you're seeking natural, progressive skin rejuvenation rather than immediate dramatic changes. It's perfect for those in their 30s-50s experiencing early to moderate aging signs, loss of elasticity, and declining skin quality. The commitment to multiple sessions and patience for results is rewarded with authentic, long-lasting enhancement that improves your skin from within.

Ready to experience Korea's latest anti-aging innovation? Research aesthetic clinics in Seoul's Gangnam or Apgujeong districts, confirm Gouri availability, and book consultations to discuss whether this revolutionary treatment aligns with your skin goals. With Korea's expertise in both developing and applying cutting-edge aesthetic technology, you're in the best possible hands for this transformative collagen-stimulating treatment.

� Medical Disclaimer: This article provides general information about Gouri PCL collagen stimulator treatments in Korea. It is not intended as medical advice and should not replace professional consultation. Individual results vary significantly based on age, skin condition, lifestyle, health status, and treatment adherence. Gouri and all collagen stimulators carry risks including but not limited to swelling, bruising, nodules, infection, and allergic reactions. Regulatory approval status varies by country. Always consult with a qualified, board-certified dermatologist or plastic surgeon before undergoing any cosmetic or medical procedure. Verify the clinic uses authentic Gouri from Dexlevo Co., Ltd. The information about prices, clinics, and treatments is current as of November 2025 and subject to change. Treatment outcomes cannot be guaranteed.

Last Updated: November 19, 2025 Reading Time: 18 minutes